Cell biology I Flashcards
What are the three constituents of the cell?
1) Organelles2) Inclusions3) Cytoplasmic matrix (cytosol)
What is the definition of cytoplasm?
The part of the cell external to the nucleus. It suspends organelles and inclusions
What is the region of the cell external to the nucleus, which suspends organelles and inclusions?
Cytoplasm
What is the definition of cytoplasmic matrix (cytosol)?
Portion of cytoplasm devoid of organelles and inclusions
What is the region of the cell that is devoid or organelles and inclusions?
Cytoplasmic matrix (cytosol)
What are inclusions?
Nonliving entities found in the cytoplasm and nucleus (e.g. food, pigments, crystalline)
Are inclusions membrane-bound?
No
Are proteins stored in the cytoplasm as inclusions?
No
Is glycogen an inclusion?
Yes
What stain would you use to detect glycogen?
PAS Reaction
What is McArdle Disease?
A disorder of glycogen storage caused by a genetic defect in muscle phosphorylase. It is specific to skeletal muscle.
McArdle Disease is specific to what type of muscle?
Skeletal muscle
Is fat an inclusion?
Yes
Is carotene an inclusion?
Yes
Is carotene fat soluble or water soluble?
Fat soluble
What is anthracosis?
Accumulation of carbon particles in lungs and regional lymph nodes. Harmless condition
Is hemoglobin an endogenous or exogenous pigment?
Endogenous
Where is hemosiderin usually found?
Macrophages of spleen and liver
What is hemosiderosis?
Increased deposition of hemosiderin in tissues
When is hemosiderosis usually observed?
1) Increased absorption of iron in diet2) Impaired use of iron by the body3) Hemolytic anemias4) Transfusions
What condition could be caused by increased absorption of iron in the diet?
Hemosiderosis