Duodote (Mark 1 Kit) Pralidoxime Chloride, Atropine

Question 1

Duodote (Mark 1 Kit) Pralidoxime Chloride, Atropine

Class:

Answer 1

parasympatholytic, Acetylcholinesterase

Question 2

Duodote (Mark 1 Kit) Pralidoxime Chloride, Atropine

Mechanism of Action:

Answer 2

Pralidoxime Chloride attaches to site where cholinesterase inhibitor is attached. Atropine is a parasympatholytic and reverses SLUDGEM.

Question 3

Duodote (Mark 1 Kit) Pralidoxime Chloride, Atropine

Indications:

Answer 3

Treatment of suspected organophosphate poisonings. Asses for SLUDGEM and killer B’s.

Question 4

Duodote (Mark 1 Kit) Pralidoxime Chloride, Atropine

Contrindications:

Answer 4

None in emergency setting.

Question 5

Duodote (Mark 1 Kit) Pralidoxime Chloride, Atropine

Precautions:

Answer 5

Does NOT work prophylactically. Use with extreme caution.

Question 6

Duodote (Mark 1 Kit) Pralidoxime Chloride, Atropine

Side Effects:

Answer 6

Hypertension .

Question 7

Duodote (Mark 1 Kit) Pralidoxime Chloride, Atropine

Interactions:

Answer 7

None relevant.

Question 8

Duodote (Mark 1 Kit) Pralidoxime Chloride, Atropine

Dosage:

Answer 8

Atropine (2.1 mg/o.7ml) Pralidoxime Chloride (600mg/2ml)

each medication is in separate internal chamber.

Question 9

Duodote (Mark 1 Kit) Pralidoxime Chloride, Atropine

Route:

Answer 9

Auto-injector, Intramuscularly (IM)

Question 10

Duodote (Mark 1 Kit) Pralidoxime Chloride, Atropine Onset:

Answer 10

3-5 minutes.

Question 11

Duodote (Mark 1 Kit) Pralidoxime Chloride, Atropine

Notes:

Answer 11

If medications are supplied separately, Atropine MUST be given first.

Question 12

Duodote (Mark 1 Kit) Pralidoxime Chloride, Atropine

Fact:

Answer 12

In an MCI save the doses for you and your partner.

Question 13

Duodote (Mark 1 Kit) Pralidoxime Chloride, Atropine

NH Notes:

Answer 13

Approved for EMT’s, can be given to pediatrics who present with life threatening symptoms with no other options.