Drugs and Treatments Flashcards

1
Q

Treatment Anxiety disorders

A

CBT

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2
Q

Meds for Anxiety

A
  1. Benzos(Gaba agonist)
    - short term use only
  2. Antidepressants( Monoamine agonist)
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3
Q

Treatments for OCD

A
  1. Behavioral therapy(Exposure and Response Prevention)

Psychosurgery- cingulotomy, capsulotomy

Deep Brain Stimulation

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4
Q

Medication for OCD

A

Antidepressants-SSRIs( increase serotonin)

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5
Q

Treatments for PTSD

A

Supportive therapy

Behavioral therapy

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6
Q

Medication for PTSD

A

Antidepressants

Benzos

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7
Q

MDD Treatment

A

Cognitive Behavioral therapy

ETC ( dont do if have vascular disease)- frontotemporal or bilateral(more effective) -induces seizures

Repetitive Transcranial Magnetic stimulation -prefrontal cortex

Vagus Nerve stimulation

Experimental:
Magnetic stimulation- like rTMS but induces seizures

Deep Brain Stimulation- Subcallosal cingulate white matter

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8
Q

Medication MDD

A

SSRIs(Fluoxetine, GI side effects), SNRIs (Venlafaxine, GI side effects), TCAs ( have heart side effects)

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9
Q

Medication BP1 & BP2

A

Lithium
Anticonvulsants
Antipsychotics

DO NOT GIVE ANTIDEPRESSANTS

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10
Q

Medications Delirium

A

Antipsychotics to treat symptoms

Benzos if caused by alcohol withdrawal

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11
Q

Drugs Alzheimer’s

A

3 cholinesterase inhibitors

  • donepezil
  • galantamine
  • rivastigmine

1 NMDA receptor block
-memantine

All considered ineffective

Antipsychotics- but Black box warning if used

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12
Q

Insomnia drugs

A

Sedatives (diazepam)
only for short use
-reduced slow wave

Benzos (zolpidem

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13
Q

Hypersomnolence drugs

A

Stimulants(modafinil, Provigil)

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14
Q

Narcolepsy drugs

A

Stimulants for somnolence
Antidepressants for cataplexy

Xyrem(sodium oxybate)=gamma hydroxybutyrate-treats both cataplexy and somnolence

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15
Q

Medication for sleep apneas

A

Respiratory stimulants (acetazolamide)

this is secondary to CPAP

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16
Q

N-RSAD medication

A

Benzos to decrease Slow wave sleep

17
Q

Nightmare disorder medication

A

Antidepressants to decrease REM sleep

18
Q

REM Sleep Behavior Disorder Medications

A

Benzo(Clonazepam)

NOTE: this disease is noted by violent movements and talking in REM sleep and is associated with Parkinson’s and Lewy body

19
Q

Restless legs medications

A

Anti-parkinson’s drugs to increase Dopamine

Can also give benzos and anticonvulsants

20
Q

Traditional Antipsychotics

A

Chlorpromazine( 1st one used)
Haloperidol

D2 Receptor antagonist

Improves positive symptoms

21
Q

Side Effects of Traditional Antipsychotics

A

Extrapyramidal Syndrome (EPS)

  • Dystonia
  • Parkinsonism
  • Akathisia (excessive movements)
  • Tardive Dyskinesia(repetitive purposeless movements)

Neuroleptic Malignant Syndrome(NMS)

  • tachycardia
  • delirium
  • extreme rigidity
  • death
PS all antipsychotics
are associated with 
*weight gain 
*sedation 
*sexual dysfunction
22
Q

Atypical Antipsychotics

A

Clozaril
Risperidone
Olanzapine

Antagonist of D2,D3,D2 and 5HT2A receptors

Improves positive and negative symptoms

Decreased risk of EPS

23
Q

Treatment of Schizophrenia

A

Psychotherapy

ECT- for catatonic type

NO PSYCHOSURGERY

24
Q

Treatment for Personality disorders

A

CBT

25
Q

Special treatment for Borderline disorder

A

Dialectical Behavioral Therapy (DBT)

Focuses on self-acceptance and cognitive-behavioral techniques

26
Q

Dopamine receptor blocker

A

Haloperidol-reduces the rewarding effect

27
Q

Meds for Alcohol(sedative) withdrawal

A

Diazepam- Anti-convulsive
Haloperidol- Anti psychotic
Clonidin- Anti Adrenergic

28
Q

Disulfiram

A

(Antabuse)

Inhibits enzyme that breaks down acetaldehyde (ALDH not this makes high NADH to NAD+ ratio)

29
Q

Naltrexone

A

(Revia)
Opioid receptor blocker
reduces pleasure of drinking

30
Q

Acamprosate

A

(Campral)
NMDA receptor antagonist
Reduces anhedonia of protracted abstinence, decreased alcohol craving

31
Q

Bupropion & Varenicline

A

(Zyban) and (Chantix)

Used for Nicotine addiction, both have black box warnings increased risk of suicide and erratic behavior

32
Q

Naloxone

A

Short acting opioid antagonist used for acute OD

33
Q

Naltrexone

A

Long acting opioid receptor blocker to block opioid effect if relapse occurs

34
Q

Methadone

A

used in Opioid replacement schedule II drug only available at OTP

35
Q

Buprenophine

A

used in Opioid replacement can be prescribed

36
Q

Suboxone

A

Buprenorphine+naloxone