d3.3 homeostasis Flashcards
homeostasis
maintenance of internal environment of the organisms
- variable are kept within preset limits despite fluctuations in the external environment
endocrine system mechanism [6]
- a stimulus is received (eg. high blood glucose level)
- use of hormones (eg. insulin)
- secreted into the blood
- transported to target tissues (eg. liver cells)
- hormone changes the conditions of the tissue (eg. take in glucose and convert to glycogen)
- the change is monitored through feedback (mostly negative feedback)
what secretes insulin and glucagon
Islets of Langerhans in the pancreases secrete these hormones
what cells synthesise and secrete glucagon
alpha cells
what cells synthesise and secrete insulin
beta cells
type 1 diabetes
- cant produce the sufficient amount of insulin
- beta cells are destroyed by their own immune system
why problem when blood glucose stays at a high level
- only can use simple diffusion bc glucose is polar
- too slow
- not enough insulin- channels wont open
type 2 diabetes
lack of insulin receptors or glucose channels on cell membranes
what is body temp detected by
thermoreceptors
where are thermoreceptors found
- peripheral thermoceptors can be found in the skin
- central thermoreceptors are found in the care of the body, including the hypothalamus
heat generation
– hypothalamus secretes thyrotropin releasing hormone (TRH)
- pituitary gland receives this chemical signal and releases thyroid stimulating hormone (TSH)
thyroxin
secreted by the thyroid gland when it receives thyroid stimulating hormone
thyroxin increase temp
cooling will trigger more thyroxin to be secreted, this increases metabolic rate of cells and increases body temperature
consequence of lack of thyroxin
hypothyroidism
- goiter (thyroid enlarges to try and capture iodine)
muscles when cold
- muscles contract to cause movement- generates heat
- small, involuntary muscle contractions and relaxation (shivering) can be carried out to generate heat
brown fat contains
a lot of mitochondria
- all energy is transformed into heat rather than producing atp
when body is overheated
vasodilatation- - circular muscle cells in the walls or arterioles (thinner than arteries but thicker than capillaries) supplying the skin relax → arterioles widen
- more blood flows to the skin → warms up to core temperature
- increased temp difference between skin and external environment causes more heat to be lost from the body
- only the amount of blood flowing through capillaries in the skin can be varied
vasoconstriction
- when circular muscle contracts- circumference of arteriole is reduced and lumen along the blood flows is narrowed
- less blood flows to the region supplied by the arteriole
- reduce heat loss- vasoconstriction of arterioles supplying the skin
- less blood flows to capillaries in the skin and cools below core body temperature
- with reduced temperature difference between the skin and external environment- less heat is lost from the body
arterioles
branches of arteries that supply blood to part of an organ
what are walls of arterioles
ring of muscle
sweating
- secreted by glands in the skin and passes through narrow ducts to the skin surface, where water in the sweat evaporates
- solutes in the sweat (ions: sodium) left on the skin surface
- water has a high latent heat of vaporisation so its evaporation causes significant cooling
- blood flowing through the skin loses heat and can then cool other parts of the body
hair erection
- air between the hairs acts as a thermal insulator
- erector muscles can move the hairs to make the coat thicker and the insulating effect greater
- human- only a few short hairs so erector muscles can still make the hairs stand up but they dont trap air well enough to insulate the body
- goose-bumps: ineffectual response to cold
hormone in kidney + function
ADH
osmoregulation
excretion
removal from the body of waste production of metabolism