Chapter 9 Spelling Words Flashcards
plasma
- the fluid portion of blood that is essential for transporting the cellular elements around the body
- 90% water; rest is electrolytes, proteins, fats, glucose, billirubin, and gases
albumin
- a plasma protein
- 60% of the plasma proteins
- helps maintain blood volume and blood pressure
- their abundance attracts water into vessels by osmosis
edema
the swelling of the tissues (because of fluid seeping out of the blood into the interstitial tissues)
globulin
- a plasma protein made by the liver and helps the synthesis of antibodies
- 36% of the plasma proteins
- three types=alpha, beta, gamma
- alpha and beta globulins=transport lipids and fat-soluble vitamins in the blood
- gamma globulins=the antibodies that function in immunity
fibrinogen
- Factor I
- a plasma protein converted into fibrin in the presence of calcium ions
- 4% of all plasma proteins
- largest plasma protein
- essential in the process of blood clotting, coagulation
differentiation
- a cell becomes specialized in function, each having a different purpose
- 3 classifications-erythrocytes, leukocytes, & thrombocytes
erythrocyte
- tiny biconcave shaped disk that is thinner in the center (to allow for the bonding of oxygen) than around the edges
- mature red blood cells (RBCs)
- no nucleus
- 120 day lifespan
- hemoglobin is the main component
- the most numerous formed element in blood
hemoglobin
- the main component of a RBC
- consists of heme and globin
- carries oxygen and carbon dioxide
leukocytes
- larger than erythrocytes but fewer in number
- white blood cells (WBCs)
- does have a nucleus
- does not possess hemoglobin
- Their are five types in two categories (neutrophils, eosinophils, basophils, monocytes, and lymphocytes)
granulocytes
- a group of leukocytes —-neutrophils, eosinophils, and basophils
- they have granules in their cytoplasm that absorbs dies
neutrophils
- 60-70% of all WBCs
- multi-lobed nuclei
- phagocytic, they respond to infections and tissue damage by engulfing and destroying bacteria
- do not absorb acid or base dye well, remain neutral colored
eosinophils
- 2-4% of WBCs
- have a nucleus with 2 lobes
- increase in numbers in response to an allergic reaction
- stain a rosy red
basophils
- secrete histamine during allergic reactions
- secrete heparin
- have a nucleus with 2 lobes
- 1% of all WBCs
- stain a dark blue with base dye
monocytes
- 3-8% of all WBCs
- the largest WBC
- kidney bean shaped nucleus
- phagocytic
lymphocytes
- 20-25% of all WBCs
- large, spherical-shaped nucleus
- play an important role in the immune process; some are phagocytic and others produce antibodies to destroy bacteria
thrombocyte
- a platelet
- small disk shaped fragment of a megakaryocyte
- contain no hemoglobin
- essential for normal coagulation
- numbers average 200,000-500,000
antigens
- also called an agglutinogen
- a substance on a RBC that can stimulate the body to make antibodies
- usually a protein and reacts specifically with the antibody it caused formation of
antibodies
- produced by the body in response to bacteria, viruses, or other foreign substances
- a substance present in the plasma that reacts in some way with the antigen that stimulated its formation
- once established, they are programmed to recognize the antigen as “foreign to the body” and will “attack it” it they come in contact with it again
agglutination
clumping of the red blood cells as a result of interaction with specific antibodies
coagulation
- the clotting of blood
- the process of transforming a liquid into a solid, especially of blood
allergen
a substance that can produce a hypersensitive reaction in the body
allergy
a hypersensitive reaction to normally harmless antigens, most of which are environmental
anaphylaxis
an exaggerated, life-threatening hypersensitivity reaction to a previously encountered antigen
anisocytosis
a condition of the blood where the RBCs are of variable and abnormal size
aniso=unequal cyt/o=cell -osis=condition
ascites
an abnormal intraperitoneal accumulation of fluid containing large amounts of protein and electrolytes
bilrubin
orange-yellow pigment of bile formed principally by the breakdown of hemoglobin in red blood cells after termination of their normal life span
corpuscle
any cell of the body, red or white
dyscrasia
an abnormal condition of the blood or bone marrow, such as leukemia, aplastic anemia, or prenatal Rh incompatibility
electrophoresis
the movement of a charged particle through a liquid medium in response to changes in an electric field; the particles of certain substance will migrate in a predictable direction and speed
electr/o-electrical; electricity -phoresis=transmission
erythremia
an abnormal increase in the number of RBCs
erythr/o=red -emia=blood condition
erythroblast
immature RBC
erythr/o-=red -blast=immature cell
erythropoiesis
the process of RBC production
erythr/o=red -poiesis=formation
erythropoietin
a hormone, synthesized in the kidneys and released in the blood stream in response to anoxia (lack of oxygen)
-the hormone stimulates and activates the production of the erythrocytes thereby increasing the blood’s capacity to carry oxygen
fibrin
an insoluble protein that is the substance of a blood clot
globin
a group of 4 globulin protein molecules that become bound by the iron in heme molecules to form hemoglobin
hematologist
a medical specialist in the field of hematology
hematology
the study of blood and blood-forming tissues
heme
iron; binds with and carries oxygen in the RBCs, and releasing it to tissues that give off excess carbon dioxide
hemolysis
the breakdown of RBCs and the release of hemoglobin that occurs at the end of the life span of the red cell
hem/o=blood -lysis=destruction or detachment
hemorrhage
the loss of a large amount of blood in a short period of time, internally or externally; may be arterial, venous, or capillary
hem/o=blood -rrhage=excessive flow or discharge
hemostasis
the termination of bleeding by mechanical or chemical means or by coagulation in the body
hem/o=blood -stasis=stopping or controlling
heparin
a naturally occurring anti-clotting factor in the body
hyperalbumininemia
an increased level of albumin in the blood
hyper=excessive albumin/o=protein/albumin
-emia=blood condition
hyperbilirubinemia
higher than normal levels of bile pigment, bilirubin in the blood
hyperlipemia
excessive levels of blood fats, usual caused by a lipoprotein lipase deficiency or a defect in the conversion of low-density lipoproteins to high-density lipoproteins; also called hyperlipidemia
hyperlipidemia
same as hyperlipemia
leukocytopenia
abnormal decrease in the number of WBCs to lower than 5,000 per cubic millimeter
megakarocyte
an extremely large bone marrow cell
myeloid
of or pertaining to the bone marrow or the spinal cord
pancytopenia
a decrease in the number of red blood cells, white blood cells, and platelets
pan=all cyt/o=cell -penia=deficiency
platelet
a clotting cell; a thrombocyte
prothrombin
- Factor II
- a plasma protein precursor of thrombin
- synthesized in the liver if adequate vit. K is present
reticulocyte
an immature erythrocyte consisting of a meshlike pattern of threads and particles at the former site of the nucleus
septicemia
systemic infection where pathogens are present in the circulating bloodstream, they spread from an infection some where in the body
seroconversion
a change in serologic tests from negative to positive as antibodies develop in reaction to an infection or vaccine
serology
the branch of lab medicine that studies blood serum for evidence of infection by elvaluating antigen-antibody reactions