Chapter 9 and 10 Immunity Flashcards
Order of frequency of immune cells
Neutrophils Lymphocytes Monocytes Eosinophils Basophils
Which 3 immune cells occur in tissue not in blood
Macrophages, dendtritic cells, and mast cells
Mononuclear phagocytes: 3
What becomes something different when leaves blood
Monocytes become macrophages
Dendritic cell
Polymorphonuclear leukocytes/granulocytes
4
Neutrophil
Basophils
Eosinophils
Mast cell
Lymphocytes
3
B cell, T cell, natural killer cells
Myeloid cells
- where they are
- what kind of immunity
- they look for what
- examples
ECF/Humoral
Innate
Non host epitopes
Neutrophils, basophils, mast cells, eosinophils, macrophages
NK cells
- where they are
- what kind of immunity
- they look for what
Cell mediated/intracellular
Innate
MHC existence
B cells
- where they are
- what kind of immunity
- they produce what
- examples 2
Humoral/extracellular
Adaptive
Antibodies
APCs and Th cells
Tc cells
- where they are
- what kind of immunity
- how they work
- examples
Intracellular/cell mediated
Adaptive
Cytotoxic to own cells, kill virus once invaded
MHC1-TCR
Where we don’t have lymph nodes
Lymph node for blood
Where T cells made
Biggest lymph organ
Brain and kidney
Spleen
Thymus
GI tract
B cells and T cells
Similarities: 1
Differences: 3
Gene arrangement to make cell
Differences:
- T cell has 2 binding sites, B cell has one
- T cell receptor on surface of T cell, B cell can have independent receptors floating around
- Antibody has something bind to its feet, T cell has MHC hand antigen to It
Class I MHCs
How many you have
HLA A, HLA B, HLA C
6 total, 1 of each type from each parent
Class II MHCs
Types
How many you have
HLA DR, HLA DP, HLA DQ
6 total, 1 from each parent also
APCs 3
B cells
Macrophages
Dendritic cells
Where T cells don’t go (immune privileged) 5
Placenta/fetus
Testes and ovaries
Eyes
Brain
Thymus
