Chapter 1 Fluid Flashcards
What moves through membrane easily (2) and what moves slowly (1)
Oxygen and co2
Water
How to calculate total body water
Weight in kg times 0.6= L
How much of TBW is intracellular
2/3, 40% of body weight
Of TBW how much is extra cellular
1/3 or 20%
What comprises extra cellular fluid, and what proportions
Interstitial fluid (75% of ECF, 15% TBW)
Plasma/intravascular fluid (25% ECF, 5% TBW)
Half of body weight is
Water inside cells
Red blood cells represented by
ICF
Plasma/extra cellular cations (2) and anions (3)
Na (140), K (5)
Cl- (104), HCO3- (24), A- (14)
A- refers to proteins that are anions
Interstitial fluid cations (2) and anions (2)
Na (145) and K (5)
Cl- (117), HCO3- (27)
Intracellular fluid cations (2) and anions (4)
K (135) Na (11)
Misc/phosphates (80), A- (54), HCO3- (10), Cl- (8)
Primary ECF cation, primary ICF cation
Sodium, potassium
Difference in cations between compartments maintained by what
Sodium (3) potassium (2) ATPases. Sodium out potassium in
At arterial end of capillary net force is what, and what happens
Higher net hydrostatic pressure +10, pushing out
What happens at venous end of capillary, net filtration
Pressure drops, higher net oncotic pressure -8, more pressure pulling back in
Conditions that cause edema
- high hydrostatic pressure venous end that won’t pull solutes back in (CHF-lungs, liver-spleen), right sided HF (feet)
- decrease oncotic pressure (portal hypertension in liver pts, not making albumin)
- damage to vessel lining- protein leak
- anaphylaxis (fluid from ICF to ISF leads to hypotension from vascular volume decrease)
- can’t drain interstitial fluid- lymph obstruction