Chapter 5 Flashcards
What is gender differentiation?
Fertilized off either carries XX or XY chromosomes
-some atypical chromosomal configurations possible
What are hormones?
Chemicals manufactured by the endocrine glands and secreted into bloodstream
What are the 2 kinds of hormone responses?
Quick acting effects
-sexual response
Slower, longer lasting effects
-Blood sugar regulation
What is the difference between the sec chromosomes?
They carry info about how to differentiate in the course of development
Where does fertilization normally occur?
Initial fertilization in distal end of Fallopian tube
Before 7 weeks can you determine if the embryo is a boy and a girl?
Before 7 weeks male and female are identical in structure and are undifferentiated
What happens at the 7th week in male and females?
Chromosomes direct gonads to begin differentiation
Male: undifferentiated gonad develop into testes around week 7
Females: ovaries develop around week 10-11
What are the 2 ducts called?
Wolffian: Male
Mullerian: Women (default)
What is the SRY?
Sex determining region Y chromosome
-if present causes testis determining factor (TDF) to be manufactured and sends message to the mullein ducts that we don’t need them
What happens if SRY isn’t present?
Female gonads develop
What are the key components to help male differentiaiton?
Presence of androgens
- testosterone
- dihydrotestosterone (DHT)
How do you get DHT?
5% of testosterone is converted
In females, what is involve in the further development of the Mullerian ducts into female structures?
Ovaries are involved
-Fallopian tubes, uterus, upper vaginal canal
Wolffian ducts will degenerate
What do the testes secrete?
Mullerian Inhibiting Substance (MIS)
What is MIS?
Causes the degeneration of the mullein ducts that are present in the undifferentiated state of XX and XY embryos
Why do testes secrete testosterone?
To support the further differentiation of the wolddian ducts into male structures
-such as epididymis, vas deferens, ejculatory duct
What is a homologous organ?
Make and female organs develop from the same embryonic tissue
What is an analogous organ?
Male and female have similar function
Where do ovaries begin and when do they move?
Begin at top of abdominal cavity in early gestational development
Week 10 gestation ovaries move down the upper edge of pelvis
-still able where they will be after birth
Where do testes begin and when do they move?
Begin at top of abdominal cavity early in gestational development
Descend through the inguinal canal to ultimate destination in scrotum
What is Cryptorchidism?
Undescended teses
- occur in 2% of males
- Associated with health issues
- impair sperm production later in life
- Increase risk of hernia and cancer
Why is Cryptorchidism associated with health issues?
Undescended testes can become twister in the abdomen
-testicular torsion
Why is Cryptorchidism associated with impaired sperm production?
Intra-abdominal temp too hot and not conducive to sperm viability
How do you treat cryptorchidism?
Surgery at 1 year
What is a hernia?
Something that is somewhere where it isn’t supposed to be
When can men get hernias?
Men with a history of undescended tests and or abdominal surgery will be monitored for hernias throughout their lifetime