Chapter 20 - Acid / Base Balance Flashcards
Three mechanisms for regulating the pH of body fluids
Buffer mechanism in blood, respiratory mechanism, urinary mechanism
Carbonic acid
Combination of water and CO2. Accelerated by carbonic anhydrase. H2CO3
Physiological pH control
Lungs and kidney response to CO2. Lungs in 1-2 minutes. Kidneys 24 hours
Buffers
Chemical substances that prevent a sharp change in the pH of fluids
Buffer pairs
Consist of two kinds of substances that interact. Main blood buffer is baking soda and carbonic acid
Metabolic acidosis
Bicarbonate deficit. Patients often suffer renal disease, uncontrolled diabetes, prolonged diarrhea, or have ingested toxic chemicals.
Metabolic alkosis
Can results from diuretic therapy, loss of gastric fluid from vomiting or suction, or from certain diseases like Cushing syndrome.
Respiratory acidosis
Caused most frequently by hypoventilation. Causes include depression of the respiratory center by drugs or anesthesia. Also respiratory diseases such as emphysema or pneumonia. Also follows cardiac arrest.
Respiratory alkosis
Hyperventilation leads to a deficit of carbonic acid caused by an excessive loss of CO2. Anxiety, over ventilation of patients on ventilators, or hepatic come can be symptoms.