Chapter 19 Flashcards
The three functions of blood?
- Transportation
- Regulation
- Protection
PH of blood?
7.35-7.45
Buffy coat?
The layer between the packed red blood cells and plasma in centrifuged blood
Describe blood plasma?
Straw coloured liquid, made up about 91. 5% water and 8.5% solutes
Where are most of the plasma proteins synthesized and what are they?
Synthesized in the hepatocytes (liver) and include albumin, globulins, fibrinogen
Antibodies
Developed by blood cells, also called gamma globulins,produced during immune responses
What are the three formed elements of blood?
- Red blood cells
- White blood cells
- Platelets
What are the types of white blood cells?
- Neutrophils
- Basophils
- Eosinophils
- Monocytes
- Lymphocytes
How can lymphocytes be further divided?
B lymphocytes, T lymphocytes, natural killer
Hematocrit
Percentage of total blood volume occupied by RBC’s
Normal range: female 38-46%, male 40-54%
Pluripotent stem cells
.05-.1% of red bone marrow that is derived from mesenchyme and have the capacity to develop into many different cells
Myeloid stem cells
Developed by pluripotent stem cells and give rise to red blood cells, platelets, monocytes, neutrophils, eosinophils, basophils and mast cells
Lymphoid stem cells
Produced by pluripotent stem cells and give rise to lymphocytes which give rise to natural killers
Hemoglobin
Globin- four polypeptide chains
Heme - ring like none protein pigment bound to each chain with an iron in the centre that can reversibly bind with an oxygen
Ferritin
Iron storage protein
Transferrin
Transporter for Fe3+ in the bloodstream
Reticulocyte
Immature red blood cell
White blood cell
Also called leukocyte, has a nuclei and other organelles but have no hemoglobin
Granular leukocytes
Neutrophils, eosinophils, basophils
A granular leukocytes
Lymphocytes, monocytes
Leukocytosis
Increase in WBC above 10,000/ul
Leukopenia
Abnormally low WBC below 5,000 ul
Selectins
Adhesion molecules displayed by endothelial cells in response nearby injury and inflammation
Hemostasis
Sequence of responses to stop bleeding