chapter 18 Flashcards
endocrine system
endocrine glands
secrete their hormones directly into bloodstream
exocrine
send chemical substances (tears, sweat, milk, saliva) via ducts to the outside of the body
posterior pituitary (neurohypophysis)
stores & releases hormones synthesized in hypothalamus
adrenal cortex (outer portion)
outer section of each adrenal glands; secretes cortisol, aldosterone & sex hormones
adrenal medulla (inner portion)
inner section of each adrenal gland; secretes epinephrine & norepinephrine
ovaries
located in lower abdomen of female; responsible for egg production & estrogen progesterone secretion
pancreas
located behind the spleen; secretes insulin & glucagon
parathyroid glands
four small glands on the posterior of thyroid gland; secretes parathyroid hormone (PTH)
pituitary gland (hypophysis)
located at the base of the brain in the sella turcica; oxytocin, ADH(vasopressin), prolactin, GH (somatotropin), thyroid-stimulating, adrenocorticotropic
testes
two glands enclosed in the scrotal sac of a male; responsible for sperm production & testosterone
thyroid gland
located in the neck on either side of the trachea; secretes thyroxine, triiodothyronine & calcitonin
epinephrine (adrenaline)
secreted by the adrenal medulla; increases heart rate, blood pressure, dilates bronchial tubes, releases glucose from storage
adrebocortocotropic hormone (ACTH)
secreted by the anterior lobe (adenohypophysis) of the pituitary gland; stimulates secretion of hormones from adrenal cortex
aldosterone
secreted by adrenal cortex; reabsorption of sodium & exceretion of potassium
androgen
male hormone secreted by the testes & adrenal cortex (to a lesser extent)
antidiuretic hormone (ADH)
secreted by the posterior lobe (neurohypophysis) of the pituitary gland; increases reabsorption of water by kidneys
calcitonin
secreted by the thyroid gland; stimulates calcium to leave the blood & enter bone & decreases blood calcium levels
cortisol
secreted by the adrenal cortex; increases blood sugar
estradiol
develops and maintains female sex characteristics; estrogen
estrogen
female hormone secreted by the ovaries & adrenal cortex (to a lesser extent); maintain menstrual cycle, release ovum, secondary sex characteristics
follicle-stimulating hormone (FSH)
secreted by the anterior lobe (adenohypophysis) of the pituitary; stimulates hormone production & egg production by ovaries & sperm production by testes
glucagons
secreted by alpha islet (Langerhans) cells of the pancreas; increases blood sugar & promotes the movement of glucose into the blood by breaking down glycogen stored in liver cells
growth hormone (GH), somatotropin
secreted by anterior lobe (adenohypophysis) of pituitary; stimulates growth of bones & soft tissues
insulin
secreted by beta islet (Langerhans) cells of pancreas; promotes movement of glucose into cells, promotes storage as glycogen
luteinizing hormone (LSH)
secreted by the anterior lobe (adenohypophysis) of pituitary gland; stimulates contraction of uterus during labor & childbirth
norepinephrine
secreted by the adrenal medulla; constricts vessels to raise blood pressure
oxytocin (OT)
secreted by posterior lobe of pituitary (neurohypophysis); stimulated contraction of uterus during labor & childbirth
parathormone (PTH)
secreted by parathyroid glands; increases blood calcium/causes calcium to mobilize from bones into bloodstream
progesterone
secreted by the ovaries; prepares uterus for pregnancy
prolactin (PRL)
secreted by anterior lobe (adenohypophysis) of pituitary; promotes milk secretion
somatotropin (STH) or GH
secreted by anterior lobe of pituitary; stimulates growth of bones & soft tissues
testosterone
male hormone secreted by testes; maintains germ cell formation & secondary sex characteristics
thyroid-stimulating gland (TSH), thyrotropin
secreted by anterior lobe (adenohypophysis) of pituitary; promotes thyroid function
thyroxine (T4), tetraiodothyronine
secreted by the thyroid gland; increases cell metabolism & uptake of oxygen
triiodothyronine (T3)
secreted by the thyroid gland; increases cell metabolism & uptake of oxygen
vasopressin or ADH
secreted by posterior lobe (neurohypophysis) of pituitary, raises water reabsorption & raises blood pressure
catecholamines
hormones derived from an amino acid & secreted by adrenal medulla
electrolyte
mineral salt found in blood & tissues
glucocorticoid
steroid hormone derived from cholesterol secreted by adrenal cortex; regulates glucose, fat & protein metabolism (cortisol) & anti-inflammatory (cortisone)
homeostasis
tendency of an organism to maintain a constant internal enviroment
hormone
substance secreted by an endocrine gland to influence structure or function of an organ or gland
hypothalamus
region of the brain lying below the thalamus & above pituitary gland
minneralcocorticoid
steroid hormone secreted by adrenal cortex to regulate mineral salts, electrolytes & water balance in the body
receptor
cellular or nuclear protein that binds to a hormone so that a response can be elicited
sella turcica
cavity in the skull that contains the pituitary gland
sex hormones
steroids produced by the adrenal cortex to influence male & female sexual characteristics
steroid
complex substance related to fats and of which many hormones are made
sympathomimetic
pertaining to minimizing or copying the effect of the sympathetic nervous system
target tissue
cells of an organ that are affected or stimulated by specific hormones
aden/o
gland
adrenal/o
adrenal glands
gonad/o
sex glands
pancreat/o
pancreas
parathyroid/o
parathyroid gland
pituitar/o
pituitary gland; hypophysis
thyr/o
thyroid gland
thyroid/o
thyroid gland
andr/o
male
calc/o & calici/o
calcium
cortic/o
cortex, outer region
crin/o
secrete
dips/o
thirst
estr/o
female
gluc/o & glyc/o
sugar
home/o
sameness
hormon/o
hormone
kal/i
potassium
lact/o
milk
myx/o
mucus
natr/o
sodium
phys/o
growing
somat/o
body
ster/o
solid structure
toc/o
childbirth
toxic/o
position
ur/o
urine
-agon
assemble, gather together
-emia
blood condition
-in & -ine
substance
-tropin
stimulating the function of
-uria
urine
eu-
good, normal
hyper-
excessive, above
hypo-
deficient, below
oxy-
rapid, sharp, acid
pan-
all
poly-
much or increased
tetra-
four
tri-
three
goiter
enlargement of thyroid
A1C
blood test that measures glycosylated hemoglobin (HbA1C) to asses glucose control
ACTH
adrenocorticotropic hormone
ADH
antidiuretic hormone
Ca+
calcium
CGMS
continuous glucose monitoring system
DI
diabetes inspidus
DKA
diabetic ketoacidosis
DM
diabetes mallitus
FBG
fasting blood sugar
FSH
follicle-stimulating hormone
GH
growth hormone
GTT
glucose tolerance test
HBA1c or A1c
test for presence of glucose attached to hemoglobin
hCG or HCG
human chorionic gonadotropin
IGF
insulin-like growth factor
LH
luteinizing hormone
MDI
multiple daily injection
OT, OXT
oxytocin
PRL
prolactin
PTH
parathyroid hormone (parathormone)
RAI
radioactive iodine
RIA
radioimmunoassay
RAIU
radioactive iodine uptake (imaging test or scan)
SIADH
syndrome of inappropriate antidiuretic hormone
SMBG
self-monitoring of blood glucose
STH
somatotropin
T3
triiodothyronine
T4
thyroxine/ tetraiodothyronine
TFT
thyroid function
TSH
thyroid-stimulating hormone
gonadotropic hormones
follicle-stimulating hormone (FSH) & luteinizing hormone (LH)
Cushing syndrome
hypersecretion of cortisol from the adrenal cortex; obesity, moonfaced, thoracic fat deposition
tetany
hyposecretion of parathyroid hormone from the parathyroid gland; constant muscle contraction
graves’ disease
hypersecretion of thyroxine from the thyroid gland
diabetes insipidus
hyposecretion of antidiuretic hormone from the neurohypophysis of pituitary; causes the body to make large amounts of urine and can lead to extreme thirst
acromegaly
hypersecretion of growth hormone from the adenohypophysis; enlargement of the extremities (after puberty)
myxedema
hyposecretion of thyroxine from the thyroid gland; swelling and thickening of the skin
diabetes mellitus
hypersecretion of insulin from the pancreas; a group of diseases that affect how the body uses blood sugar (glucose)
addison’s disease
hyposecretion of aldosterone (cortisol) from the adrenal cortex; low blood sugar, darkness of skin, fatigue, deficient in mineralocorticoids & glucocorticoids, hyponatremia
gigantism
hypersecretion of growth hormone from adenohypophysis; person grows very tall (up to 8ft)
endemic goiter
hyposecretion of thyroxine from the thyroid gland; occurs in iodine-deficient areas.
cretinism
hyposecretion of thyroxine from the thyroid gland; intellectual disability, small stature & thickening of the facial features
pheochromocytoma
hypersecretion of epinephrine & norepinephrine from the adrenal medulla; benign tumor of adrenal medulla, hypertension, tachycardia, palpations, severe headaches, sweating, flushing of face & muscle spasms
hypogonadism
condition of deficiency or underdevelopment of the sex organs
endocrinologist
specialist in the study of hormone disorders
hyponatremia
deficient sodium in blood
polydipsia
condition of excessive thirst
glycosuria
condition of sugar in the urine
euthryroid
normal thyroid function
hyperthyroidism
condition of increased secretion from the thyroid gland
ketoacidosis
condition of excessive ketones (acid) in blood as a result of diabetes mellitus
glycogen
animal starch, storage from of glucose
adrenal virilism
abnormal secretion of androgens from the adrenal cortex produces masculine characteristics in a female
thyroid carcinoma
cancerous tumor of thyroid gland
hirsutism
excessive hair on the body (result of hypersecretion of androgens)
type 1 diabetes
destruction of beta islet cells, insulin not produced
diabetic neuropathy in type 1 diabetes
destruction of neurons as 2nd complication of diabetes mellitus
hypoglycemia
too little sugar in blood can occur if too much insulin is taken by a diabetic patient
type 2 diabetes
insulin deficiency & resistance by target tissue to action of insulin
diabetic retinopathy
destruction of blood vessels in the retina as a secondary complication of diabetes mellitus
diabetic coma
unconsciousness caused by high levels of sugar in the blood; water leaves cells to balance the large amounts of sugar in the blood, leading to cellular dehydration
diabetic nephropathy in type 2 diabetes
destruction of the kidney as a 2nd complication of diabetes mellitus
atherosclerosis in type 2 diabetes
collection of fatty plaque in arteries
hyperglycemia
high level of sugar in the blood; insulin is unavailable or unable to transport sugar from the blood into cells
gastroparesis
decreased gastric motility, secondary complication of diabetes
insulin shock
hypoglycemic shock caused by an overdose of insulin, decreased intake of food, or excessive exercise
thyroid gland
radioactive compound is given & the thyroid is imaged using scanning device
fasting plasma glucose
measurement of blood sugar levels in a fasting patient (at least 4 hours) & after intervals of 30 minutes and 1,2 & 3 hours after ingestion of glucose
exophthalmometry
measurement of eyeball protrusion (symptoms of graves’ disease)
thyroid function test (TFT)
measurement of T3, T4 & TSH in bloodstream