ch 8 part 2 reviews Flashcards
cell cycle points
points at which progression to the next stage can be stopped
3 primary checkpoints:
G1/S: assessing DNA growth and damage
G2/M: assessing DNA synthesize
Spindle Assembly Checkpoint: is the cell ready for anaphase
complementary base pairing?
each strand contain the information needed to synthesize its complementary strand
steps :
1-parent DNA molecules
2-then saperate into two template strands
3-complimentary nucleotide bases attach to each
4-template strand
5-two identical daughter molecules
DNA Replication
Two steps:
Unwinding and separation
Reconstruction and elongation
Step 1: Unwinding and separation
Begins at the origin of the replication
DNA helicase
Replication fork
DNA helicase
-unwind the DNA
-seperate the two strand
Step 2: Reconstruction and elongation
Synthesis of the new DNA strands
each of the five carbon in the sugar is numbered
sugar phosphate backbone
DNA replication deponds on__________
base-pairing rules
Unwound sections of __________ DNA strands serve as _________ for synthesis of new complementary DNA strands
parental
templates
DNA polymerase
Adds nucleotides to the 3’-end of the growing strand
New strand is synthesized
DNA polymerases proofread their work
Mismatch repair: daughter strand repair single base pair error
Nucleotide excision repair: larger error repair
Any errors that are missed are passed onto the daughter DNA and become ______________
permanent mutations