Centromeres, centrioles and centrosomes Flashcards
A centromere is needed for…
the separation of chromatids. It is the site of attachment of spindle microtubules.
Each chromosome has two…
kinetochores at its centromere, one on each chromatid.
Kinetochores are made of…
protein molecules. which bind to DNA in the centromere and to microtubules.
Spindle fibre is…
bundle of microtubules.
Spindel fibres extend from…
kinetochores to the poles of the spindle during mitosis.
The formation of kinetochores begins…
during the S phase and they are lost after the cell division.
The microtubules attached to a kinetochore pull…
the kinetochore with the rest of its chromatid.
Dragging of chromatid is achieved by…
shortening of the microtubules, both from the pole end and from the kinetochore end.
The poles of the spindle are…
at the centrosomes. One at each pole.
Centrosome consists of…
a pair of centrioles surrounded by a large number of proteins. These proteins control the production of microtubules, not the centrioles.
