Cell signaling Flashcards
Importance of cell signalling:
All cells and organisms must be able to respond to their changing environment.
Signal pathway:
- stimulus
- receptor
- transmission of signal
- effector
- response
Transduction is…
conversion of the original signal to a message that can be transmitted
Transmitting message involves…
crossing barriers such as cell surface membranes
Signalling molecules are usually very…
small for easy transport.
Signalling includes both…
electrical and chemical events and their interactions with each other.
The cell surface membrane is critical…
component of most signalling pathways because it is a barrier to the molecules.
In typical signalling pathway, molecules…
must cross or interact with the cell surface membrane
Signalling molecules are very…
diverse.
If the signalling molecule is hydrophobic such as…
steroid hormones it can diffuse directly across the cell surface membrane and bind to receptors.
Most of the signalling molecules are…
water soluble.
(Typical signalling pathway) Starts with signal arriving…
at a protein receptor in a cell membrane.
(Typical signalling pathway)The receptor has a specific…
a shape which recognises the signal. (only cells with this receptor can recognise it)
(Typical signalling pathway)The signal brings a change in…
the shape of the receptor, this spans the membrane and message is passed to the inside of the cell. (signal transduction)
(Typical signalling pathway)The change in shape of the receptor allows…
interaction with the next component.
