Cancer 2 Flashcards

1
Q

Treatment options

A
Surgery
Radiotherapy 
Chemotherapy 
Hormonal replacement therapy 
Targeted therapy
Immunotherapy 
Stem transplant
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2
Q

Factors affecting treatment decision and response

A
Tumour type
Pre-treatment co morbodities
Tumour burden
Rate of tumour growth
Drug resistance 
Hormone receptor status
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3
Q

Surgery

And disadvantages

A

Surgical removal of the localised tumour
All or some tumour removed

Can be extensive and invasive that surrounding tissue dan be damaged

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4
Q

Radiotherapy

A

High dose x ray beam
15 min dialy appointment for 1 day to 5 weeks
Can be used concurrently with ct as a radiosensitiser or to control pain in palliative care

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5
Q

Radiotherapy disadvantages

A

Transport issues

Side effects

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6
Q

Nurse role radiotherapy

A

Education management of side effects
Pace maker monitoring
Handover admission to ward
Wound dressings

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7
Q

Tpye of radiotherapy

A

Internal

External

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8
Q

Internal

A
Brachytherapy
Implantation of radioactive materials into or close to the tumour
Reduces expose to healthy tissue 
Patrint is radioactive 
Limit the amount of time near patient
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9
Q

External and superficial

A

Most common

Ionizing radiation beam from a megavolt machine causes damage to cancer cells

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10
Q

Nusing implication

A

Education
What to expect

Intervention for side effects

Anaemia nausea and vomiting loss of appetite

Supportive care
Analgesics skin care mouth care

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11
Q

Common side effects

A
Bone marrow suppression 
Cardiovascular effects
Gastrointestinal effect
Fatigue
Pulmonary effect
Reproductive effect
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12
Q

Bone marrow suppression

A

common side of therapy of chemo

Treatment induced reduction in RBC and WBC can result inc
Infection
Haemmorrhange
Fatigue

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13
Q

Cardiovascular effect

A

Pre existing condition

Some ctx cause cardio toxicity

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14
Q

Gastrointestinal effect

A

Antiemetic
Antidiarrhoeals
Referral to dietician
Soft toothbrush

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15
Q

Fatigue

A

Encourage conversation strategies

Rest before activity
Get assistance
Maintain nutritional and hydration results
Assess for reversible causes if fatigue

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16
Q

Pulmonary effect

A

Bronchodilator
Cough suppressant
Oxygen

17
Q

Reproductive effect

A

Inform patient of expected sexual side effects
Encourage discussion of issues
Refer to counseling
Sperm banking

18
Q

Chemotherapy

A

Systematic sustemcthat may be used as single agent of combination

Inhibit cell proliferation via direct or indirect effect of DNA resulting in cell death

Dose of limiting toxicities

Preparation for stem cell transplant

19
Q

The cell cycle

A

All cell normal and neoplastic must go through cell division

Toxic to all dividing cells

Cell cycle-specific drug exert action during certain phases if cell division

Cell cycle nonspecific drug act on tumour cells in both resting and dividing phases

20
Q

Types of chemotherapy

A

AntiTumour antibiotics
Anti metabolitic
Alkylating agents
Plant alkaloids

21
Q

Anti tumour antibiotics

A

Cycle non specific. Interferes woth RN and DNA replication

Epirubicin

22
Q

Antimetabolites

A

Greatest s phase of the cell division. Inhibits protein synthesis

Methotrexate
Gemcitabine

23
Q

Alkylating agent

A

Cycle non-specific
Impairs rna and dna
Cyclophosphamide

24
Q

Plant alkaloids

A

Inhibit m-phase of the cell cycle

Paclitaxel