Blood Flashcards

1
Q

Name the 3 types of blood cells.

A

Erythrocytes (red BC)
Leukocytes (white BC)
thrombocytes (platelets)

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2
Q

List the plasma proteins (4)

A

Albumins: Maintains oncotic pressure.

Globulins: Transports molecules. Immune functions.

Fibrinogen: Blood clotting.

Regulatory proteins: Regulate enzymes and hormones.

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3
Q

What shape are red blood cells? What is the purpose of this shape.

A

Biconcave shape.
Increases the surface area for oxygen. Allows contraction and expansion of the cell so that it can get through small vessels.

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4
Q

What is the lifespan of a RBC?

A

120 days

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5
Q

What happens to damaged RBC?

A

Haemolysis occurs immediately the products are passed to macrophages to be broken down and are then peed out.

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6
Q

What is haem broken down into?

A

Biliverdin then bilirubin.

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7
Q

What is the name for RBC formation?

A

Erythropoiesis.

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8
Q

What hormone regulates erythropoiesis?

A

Erythropoietin.

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9
Q

Where is erythropoietin made?

A

The liver.

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10
Q

Where does erythropoiesis occur?

A

Red bone marrow in the skull cap, the hip, long bones and the sternum.

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11
Q

In mature RBC, what does folic acid and B12 assist the removal of?

A

The nucleus.

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12
Q

Explain the process of red blood cell production.

A

Decrease in RBC

Decrease in oxygen delivery

Decreased amount of oxygen reaching the kidney.

Causes erythropoietin to be released.

Hormone travels to red bone marrow.

Increased RBC production.

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13
Q

What enzyme allows CO2 to be carried on RBC?

A

Carbonic anhydrase.

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14
Q

Carbonic anhydrase is found in RBC, where else in the body is it found?

A

The parietal cells in the stomach.

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15
Q

What form of haemoglobin does a foetus have?

A

Hb-F

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16
Q

How many oxygen particles are in haemoglobin?

A

4

17
Q

Name the granulocytes in white blood cells.

A

Neutrophil, basophil, eosinophil.

18
Q

Name the granulocytes in white blood cells.

A

Monocytes and lymphocytes.

19
Q

What do platelets produce that assist the process of blood clotting?

A

Vasoconstrictor- thromboxane a2.

Constricts the areas, platelets block.

20
Q

What produces a blood group?

A

The protein (antigen) on the surface of red blood cells.

21
Q

If a blood group had an A antigen on the surface what antibodies would be in the blood?

A

Not A antibodies.

22
Q

What is unique about the blood type AB?

A

Has both A and B antigens on the surface.

23
Q

What is unique about blood type 0?

A

Has no antigens on he surface so can be given universally.

24
Q

What does the charge on a blood type indicate?

A

If the rhesus protein is present.

25
Q

What is haemolytic disease of the newborn?

A

If a mother is Rh negative and has a Rh positive baby the blood mixes during birth and Anti-Rh antibodies are formed.

This becomes an issue if the mother has a second child with the same father. Now that she has anti-Rh antibodies formed if the second child is Rh positive, the antibodies will attack the baby.

26
Q

What blood type is universally given in transfusion?

A

Group 0

27
Q

What blood type can receive any blood transfusion?

A

Group AB. No antibodies in their system.