Blood Flashcards
Name the 3 types of blood cells.
Erythrocytes (red BC)
Leukocytes (white BC)
thrombocytes (platelets)
List the plasma proteins (4)
Albumins: Maintains oncotic pressure.
Globulins: Transports molecules. Immune functions.
Fibrinogen: Blood clotting.
Regulatory proteins: Regulate enzymes and hormones.
What shape are red blood cells? What is the purpose of this shape.
Biconcave shape.
Increases the surface area for oxygen. Allows contraction and expansion of the cell so that it can get through small vessels.
What is the lifespan of a RBC?
120 days
What happens to damaged RBC?
Haemolysis occurs immediately the products are passed to macrophages to be broken down and are then peed out.
What is haem broken down into?
Biliverdin then bilirubin.
What is the name for RBC formation?
Erythropoiesis.
What hormone regulates erythropoiesis?
Erythropoietin.
Where is erythropoietin made?
The liver.
Where does erythropoiesis occur?
Red bone marrow in the skull cap, the hip, long bones and the sternum.
In mature RBC, what does folic acid and B12 assist the removal of?
The nucleus.
Explain the process of red blood cell production.
Decrease in RBC
Decrease in oxygen delivery
Decreased amount of oxygen reaching the kidney.
Causes erythropoietin to be released.
Hormone travels to red bone marrow.
Increased RBC production.
What enzyme allows CO2 to be carried on RBC?
Carbonic anhydrase.
Carbonic anhydrase is found in RBC, where else in the body is it found?
The parietal cells in the stomach.
What form of haemoglobin does a foetus have?
Hb-F