Biochemistry Flashcards
What is the big idea one
the process of evolution drives the diversity and unity of life
Unity
all living things made of the same five basic molecules
The basic molecules
are individual subunits of larger molecules, they are referred to as monomers or building blocks
how do monomers gain their chemical properties
from the combination and arrangement of the functional groups on the exterior of the monomer
what are functional groups
small groups of atoms that confer specific chemical traits to anything they bond to
Hydroxyl group
(-OH) makes things polar and water soluble
Carboxyl group
(-COOH) makes things acid and water soluble
Phosphate groups
(-OPO3) energizes water and makes water soluble
Amino group
(NH2) makes things bases
Methyl group
(-CH3) makes things nonpolar and insoluble
What do water soluble functional groups have in common
oxygen
Big idea 2
biological systems utilize free energy and molecular building blocks to grow, reproduce, and to maintain dynamic homeostasis
monomers
molecular building blocks, small organic molecules joined together to form larger molecules
Macromolecules
monomers covalently bonded together form giant. Any large biological molecule made by fusing together monomers
Polymer
all the monomers are the same type in the giant molecule
Macromolecules examples
triglycerides
peptides (also polymer since made up of all amino acids)
all organic molecules must have
carbon and hydrogen
hydrocarbons
only C and H
Carbohydrates
have only C, H, and O
What inorganic compounds would you expect to find in you
CO2
H2O
NACL
HCL
Why carbon based life forms
carbon can bond to 4 other atoms
bonds are strong covalent
can form double bonds, rings, and chains
what happens to ionic molecules in aqueous solution
dissociate
Bond strength in order in living systems
covalent bond >ionic bond >hydrogen bond
All living things are made of
saccharides
lipids
proteins(polypeptides)
nucleotides
Saccharides
sugars made of monosaccharides only carbohydrates all have hydroxyl most dissolve in water
monosaccharides
single monomer sugars
smallest unit of saccaharides
monosaccharide examples
gluctose
fructose
galactose
disaccharides
two monosaccarhides bonded together
disaccharide examples
sucrose- table sugar (glucose and fructose)
lactose
oligosaccahirdes
a few monosaccharides
part of glycoproteins or glycolipids
membrane receptors or identification markers
polysaccharides
many
different properties based on bonding patterns and chain shape or folding patterns
Polysaccharide examples
starch-
cellulose-
glycogen-
hydroxl facing out v. in
facing out- soluble
in- insoluble
lipids
macromolecules and grouped together due to hydrophobic nature
triglycerides
one glycerol molecule bound to three fatty acids
fats are usually solids mostly in
animals
oils are ususally liquids in —
plants
triglyceride structure
one glycerol bound to three fatty acid molecules
glycerol
an alcohol that binds up to three monomers
fatty acids
hydrocarbon chains with a carboxyl group on one end
fat
made of saturated fatty acids
no double bonds( full of H)
packed tightly so dense and solid
oil
one or more unsaturated fatty acid
not enough H to take up all bonds
double bonds make chain bend
do not pack well, less dense, liquid
How are trans fatty acids made
made by adding hydrogen to unsaturated fatty acids
partially hydrogenated oils,makes oils more solid, creates trans shaped double bonds
what is the side effects for trans fatty acids
implicated in atherosclerosis ( plaque deposits in blood vessels)and an increased risk of heart attack and stroke and upsets cholesterol levels
can our bodies make fatty acids
no so we must eat them
examples of fatty acids we need
omega 3, not enough, omega 6, more than enough
sources of fatty acids
fish, vegetables, oils
steroids
made of 4 fused carbon rings with different functional groups attached
phospholipids
glyerol bonds with 2 fatty acids and one phosphate
fatty acid tails for phospholipis are
hydrophobic
phosphate/ glycerol head for phospholipids are
hydrophilic
phospholipids are blank towards water
amphipathic, like and fear water, one end likes the other fears
waxes
long chains of fatty acids tightly packed to long chain alcohol or carbon rings, repel water
proteins (polypeptides)
polymers made of amino acid monomers
in proteins, each amino acid is a carbon bonded to a
amino group
carboxyl group
hydrogen
and one of the 20 r groups
r groups give the amino acids
characteristics (polar or non, acidic neg charge or basic plus charge)
levels of protein structure 1*
chain of aa
levels of protein structure 2*
chain of aa folds over on itself and sticks due to h bonds
levels of protein structure 3*
3D shape due to disulfide bonds
levels of protein structure 4*
> one chain of aa bonded together
denaturation of proteins
3D shape of protein altered
protein no longer functions properly,
h bonds and disulfide bonds are broken
What are largest monomer made of 3 different groups/monomers
neucleotides
nucleotides made of
a sugar (ribose or deoxyribose)
a phosphate group
a nitrogen base (A,T,G,C,or U)
nucleotides can function alone as
coenzymes that transfer electron or H+
ATP
nucleotides can form
polymers called nucleic acid (DNA/RNA)
nucleic acids
polymers of many nucleotides- covalently bonded into chains
DNA
made of nucleotides with the sugar deoxyribose
RBA
made of nucleotides with the sugar ribose
types of chemical reactions
functional group transfer electron transfer (redeox reaction) rearrangement of atoms condensation dehydration reaction hydrolysis reaction
condensation dehydration reaction
remove water ( in form of H from one molecule and OH from the other) in order to stick two molecules together
hydrolysis reaction
using water to break two molecules apart, put water in form of H and Oh back in
starch-
starch-plant glucose storage
cellulose-
plant cell walls/ fiber
glycogen-
animal glucose storage
wax examples
beeswax or plant cuticle
proteins make
makes enzymes, hormones, muscle
peptide bond
bond between amino acids
Most important steroid
Cholesterol
Cholesterol
Animal and cell membranes, precursor for steroid hormones,vitamin d and bile salts