Autonomic Nervous System Flashcards
- name implies that visceral innervation operates involuntarily on its own (in contrast to the voluntary control characteristic of somatic innervation of skeletal muscle)
Autonomic
- means self-rule/self-govern; from the Greek: auto = ____; nomos = ____
self
rule
also known as chemical messengers, are endogenous chemicals that enable neurotransmission. They transmit signals across a chemical synapse, such as a neuromuscular junction, from one neuron (nerve cell) to another “target” neuron, muscle cell, or gland cell.
Neurotransmitters
a nerve cell cluster or a group of nerve cell bodies located in the autonomic nervous system
Ganglion
branching network of intersecting nerves
Plexus
a specialized cell transmitting nerve impulses; a nerve cell.
Neuron
- The _______ ____ and ______ _____ are located within the vertebral canal of the vertebral column. Dorsal and ventral spinal roots unite to form a spinal nerve (bilaterally).
spinal cord
spinal roots
is enveloped by connective tissue (epineurium, perineurium, & endoneurium)
Spinal Nerve
composed of afferent (sensory) axons; the site of a spinal ganglion
dorsal root
composed of efferent axons that innervate muscle & gland
ventral root
Divides into four primary branches:
Ømeningeal branch
Øramus communicans
Øventral branch
Ødorsal branch
*four primary branches:
small; sensory to meninges
Ømeningeal branch
*four primary branches:
connects to sympathetic trunk & innervates viscera
Øramus communicans
*four primary branches:
largest branch; hypaxial mm. & lateral and ventral cutaneous nn.
Øventral branch
*four primary branches:
medial and lateral branches; epaxial mm and dorsal cutaneous nn.
dorsal branch
*Fiber types
axons associated with receptors and unipolar cell bodies in spinal ganglia
Afferent (sensory)
*Fiber types, Afferent (sensory)
receptors in skin & muscles, tendons, joints
- General Somatic Afferent (GSA):
*Fiber types, Afferent (sensory)
receptors in viscera
- General Visceral Afferent (GVA):
*Fiber types
axons that innervate muscle & gland; cell bodies are located in the spinal cord (or in some cases autonomic ganglia)
Efferent (motor)
*Fiber types, Efferent (motor)
innervates skeletal muscle
Somatic Efferent (SE):
*Fiber types, Efferent (motor)
innervates cardiac m., smooth m., & gland
Visceral Efferent (VE):
- Also known as the GENERAL VISCERAL EFFERENT (GVE)
- Portion of the nervous system concerned with the motor innervations of smooth muscle, cardiac muscle and glands.
Autonomic Nervous System (ANS)
GVE Pathaway involves two neurons
preganglionic neuron
postganglionic neuron
*GVE Pathaway two neurons
cell body located in CNS; axon synapses in an autonomic ganglia
preganglionic neuron
*GVE Pathaway two neurons
cell body in an autonomic ganglion; axon \ innervates smooth muscle, cardiac muscle or gland; Ordinarily occur in clusters referred to as ganglion.
postganglionic neuron
Autonomic Nervous System of PNS (?)
involuntary
Somatic Nervous System of PNS (?)
voluntary
- pathways that innervate smooth muscle, cardiac muscle, and glands involve two neurons and a synapse within an autonomic ganglion.
Two-neuron pathways
*Classification of Autonomic Ganglia
Are more or less segmentally distributed along the paired sympathetic chains which in turn lie along the ventral sides of the heads of the ribs
Vertebral ganglia
Classification of Autonomic Ganglia
Are found more peripherally and in the abdominal cavity are related to some of the larger arteries such as the celiac.
Collateral ganglia
*Classification of Autonomic Ganglia
Are usually small and located in various body organs.
Terminal ganglia
3 Classification of Autonomic Ganglia
Vertebral ganglia
Collateral ganglia
Terminal ganglia
*ANS Divisions: Sympathetic
Innervtion Distribution: ?
Preganglionic Origin: ?
Postganglionic Neuron: ?
Target Neurotransmitter: ?
Functional Role: ?
whole body
thoracolumbar spinal cord
usually adrenergic
norepinephrine
“fight or flight”
ANS Divisions: Parasympathetic
Innervtion Distribution: ?
Preganglionic Origin: ?
Postganglionic Neuron: ?
Target Neurotransmitter: ?
Functional Role: ?
body cavities & head
brainstem & sacral spinal cord
always cholinergic
acetylcholine
routine operations
Sympathetic Divisions (7)
- Overview
- Head
- Neck
- Body Wall
- Thorax
- Abdomen
- Pelvis
Overview: Sympathetic Division
- originates from _____________ ________ of the spinal cord (approximately T-1 to L-4, bilaterally)
thoracolumbar segments
- For all regions of the body, the initial pathway for sympathetic preganglionic axons is identical: (4)
ventral root
spinal nerve
ramus communicans
sympathetic trunk.
*Sympathetic Pathway to the Head
Origin:
most cranial thoracic segments (T1-T3)
*Sympathetic Pathway to the Head
Preganglionic Pathway:
ventral root, spinal nerve, ramus communicans, sympathetic trunk, ansa subclavia, cervical sympathetic trunk
*Sympathetic Pathway to the Head
Ganglion:
cranial cervical ganglion
*Sympathetic Pathway to the Head
Postganglionic Pathway:
internal and external carotid nerve plexuses, continuing plexuses named for particular vessels.
*Sympathetic Pathway to the Head
Target organs
pupillary dilator muscle; nasal glands; salivary glands; sweat glands; blood vessel smooth muscle
*Sympathetic Pathway to the Neck
Origin:
cranial thoracic segments (T3-T5)
*Sympathetic Pathway to the Neck
Preganglionic Pathway:
ventral root, spinal nerve, ramus communicans, sympathetic trunk,
*Sympathetic Pathway to the Neck
Ganglion:
cervicothoracic ganglion
*Sympathetic Pathway to the Neck
Postganglionic Pathway:
vertebral nerve rami communicantes to cervical spinal nerves dorsal or ventral primary branches
*Sympathetic Pathway to the Neck
Target Organs:
arrector pili smooth muscle (piloerection); sweat glands; blood vessel smooth muscle
*Sympathetic Path to Trunk Wall & Limbs
Origin:
thoraco-lumbar segments (T1-L4)
*Sympathetic Path to Trunk Wall & Limbs
Preganglionic Pathway:
ventral root, spinal nerve, ramus communicans, sympathetic trunk,
*Sympathetic Path to Trunk Wall & Limbs
Ganglion:
sympathetic trunk (paravertebral) ganglia
*Sympathetic Path to Trunk Wall & Limbs
Postganglionic Pathway:
rami communicantes to spinal nerves, dorsal or ventral primary branches of spinal nerves
*Sympathetic Path to Trunk Wall & Limbs
Target Organs:
arrector pili smooth muscle (piloerection); sweat glands; blood vessel smooth muscle
*Sympathetic Path to Thoracic Viscera
Origin:
mid-thoracic segments (T5-T8)
*Sympathetic Path to Thoracic Viscera
Preganglionic Pathway:
ventral root, spinal nerve, ramus communicans, sympathetic trunk, [ansa subclavia]
*Sympathetic Path to Thoracic Viscera
Ganglion:
cervicothoracic ganglion & [middle cervical ganglion]
*Sympathetic Path to Thoracic Viscera
Postganglionic Pathway:
branches from the ansa subclavia, [branches that run with the vagus nerve]
*Sympathetic Path to Thoracic Viscera
Target Organs:
heart; bronchiole smooth muscle; blood vessel smooth muscle
*Sympathetic Path to Abdominal Viscera
Origin:
thoracic & lumbar segments (T7-L2)
*Sympathetic Path to Abdominal Viscera
Preganglionic Pathway:
ventral root, spinal nerve, ramus communicans, symp. trunk, major & minor splanchnic nerves, also, lumbar splanchnic nerves
*Sympathetic Path to Abdominal Viscera
Ganglion:
prevertebral ganglia within plexuses: celiac, cranial & caudal mesenteric, gonadal, renal; also, adrenal medulla
*Sympathetic Path to Abdominal Viscera
Postganglionic Pathway:
nerve plexuses on abdominal vessels (e.g., splenic, middle colic, renal, etc.)
*Sympathetic Path to Abdominal Viscera
Target Organs:
alimentary smooth m. & glands; liver; pancreas; blood vessel smooth muscle
*Sympathetic Path to Pelvic Viscera
Origin:
lumbar segments (L1 - L3)
*Sympathetic Path to Pelvic Viscera
Preganglionic Pathway:
ventral root, spinal nerve, ramus communicans, sympathetic trunk, lumbar splanchnic nerves, caudal mesenteric nerve plexus
*Sympathetic Path to Pelvic Viscera
Ganglion:
caudal mesenteric ganglion (also, some synapse in pelvic ganglia)
*Sympathetic Path to Pelvic Viscera
Postganglionic Pathway:
left/right hypogastic nerve to pelvic plexus,
pelvic plexus branches to pelvic viscera
*Sympathetic Path to Pelvic Viscera
Target Organs:
pelvic viscera smooth muscle & glands: urinary, genital, rectum & anal canal; blood vessel smooth muscle
Overview: Parasympathetic Division (3)
- Sacral parasympathetic
- Vagal parasympathetic
- Brainstem parasympathetic
- Unlike the ANS, it does not arise from the brain stem or spinal cord
- Like the ANS, innervates smooth muscles and glands
- Consist of millions of neurons embedded in the wall of the digestive tract.
ENTERIC NERVOUS SYSTEM
what are the two Forms of Plexi
Myenteric plexus (Auerbach)
Submucosal plexus (Meissner’s)
*Plexi
Lies between layers of longitudinal and circular muscles of the alimentary canal
Myenteric plexus (Auerbach)
*Plexi
Lies between submucosal layer of intestines, from the junction with the stomach to the anus.
Submucosal plexus (Meissner’s)
The enteric nervous system Controls the activity of the GIT in three ways:
- Controlling intestinal peristalsis
- Modulating blood flow through gut
- Regulating the release of secretions from the gastrointestinal tract.