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Pharma > Antiadipositas > Flashcards

Antiadipositas Flashcards

1
Q

Gruppe von Orlistat

A

Lipase-Hemmer

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2
Q

Indikation von Orlistat

A

Adipositas

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3
Q

Wirkungsmechanismus von Orlistat

A

-Hemmung der Lipase im GIT-> verminderte Fettresrption (TAGs nicht in Mizellen)
-Verminderte Fettresorption
-Cholisteron schlechter resorbiert
-Verringerte Resorption von fettlöslichen Vitaminen
-Hemmung pankreatische Carboxylester-Lipase

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4
Q

Wirkung von Orlistat

A

Gewichtsreduktion um circa 5% (chronische Gabe)

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5
Q

Nebenwirkungen von Orlistat

A

-GIT-Störungen
-Kopfschmerzen
-Angstgefühl. Panikattacken
-Menstruationsbeschwerden
-Zunahme Atem- und Harnwegsinfekte

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6
Q

Interaktionen von Orlistat

A

-verminderte Resorption von anderen Medikamenten
- verminderte Resorption von fettlöslichen Vitaminen

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7
Q

Gruppe von Tirepatid

A

GCP-1/GIP-Analogon

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8
Q

Indikation von Tirepatid

A

Adipositas

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9
Q

Wirkungsmechanismus von Tirepatid

A

Wirkt als Analogon am:
-Gehirn -> Hungergefühl sinkt
- Pankreas-> Insulin steigt
-Magen -> Magenentleerung sinkt

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10
Q

Wirkung von Tirepatid

A

Gewichtsverlust
D2-Kontrolle

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11
Q

Pharmakokinetik

A

BV: circa 80

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12
Q

Gruppe von Bupropion/Naltrexon

A

Selektive Dopamin-/Noradrenalin Rückaufnahme-Hemmer und Opioidrezeptor-Antagonist

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13
Q

Indikation von Bupropion/Naltrexon

A

Adipositas

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14
Q

Wirkungsmechanismus von Bupropion/Naltrexon

A

Rückresorption von Noradrenalin und Dopamin wird verhindert

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15
Q

Wirkung von Bupropion/Naltrexon

A

Gewichtsverlust

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16
Q

Nebenwirkungen von Bupropion/Naltrexon

A

HF und BP steigen

Pharma (11 decks)

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