anotha cc

Question 1

paired, bean-shaped organs

Answer 1

kidneys

Question 2

functional unit of each kidney

Answer 2

nephron

Question 3

TEST FOR GLOMERULAR FILTRATION RATE Glomerular Filtration Rate (GFR)

Answer 3

1. Clearance
   a. Inulin Clearance (Reference Method)
   b. Creatinine Clearance
   c. Urea Clearance
2. Cystatin C
3. β-trace protein

Question 4

TEST FOR RENAL BLOOD FLOW

Answer 4

1. Blood Urea Nitrogen (BUN)
2. Creatinine
3. Blood Uric Acid (BUA)

Question 5

Measure of the clearance of normal molecules that are not bound to protein and are freely filtered by the glomeruli neither absorbed nor secreted by the tubules.

Answer 5

Glomerular Filtration Rate

Question 6

best overall indicator of the level of kidney function

Answer 6

GFR

Question 7

liters of glomerular filtrate is produced daily.

Answer 7

150

Question 8

It is the removal of the substance from plasma into urine over a fixed time.

Answer 8

Clearance

Question 9

It represents the volume of plasma that would contribute all the solute excreted

Answer 9

clearance

Question 10

It is expressed in

Answer 10

mm/min

Question 11

II. TEST FOR RENAL BLOOD FLOW

Answer 11

1. Blood Urea Nitrogen (BUN)
2. Creatinine
3. Blood Uric Acid (BUA)

Question 12

Plasma concentration and clearance are

Answer 12

inversely proportional

Question 13

It is not routinely done because of the necessity for continuous IV infusion

Answer 13

Inulin Clearance

Question 14

Based on the concept that once a marker has reached a steady state in the plasma and the volume of distribution is saturated, the rate of elimination of the marker will equal the rate of infusion (RI)

Answer 14

Plasma Inulin Clearance

Question 15

Continuous Infusion Method

Answer 15

Plasma Inulin Clearance

Question 16

requires an intravenous infusion and timed urine collection over many hours

Answer 16

Inulin Clearance

Question 17

is a breakdown product of dietary meat and creatine phosphate found in skeletal muscle.

Answer 17

Creatinine

Question 18

it is also secreted by the peritubular capillaries, causing CrCl to overestimate the GFR by approximately

Answer 18

10% to 20%.

Question 19

specimen for crcl

Answer 19

Serum and urine samples are required. The serum collection must be within 24 hours of urine collection

Question 20

A blood sample of ___ ml

Answer 20

1mL

Question 21

Normal range

Answer 21

◦ 110 to 150mL/min in males
◦ 100 to 130mL/min in females.

Question 22

is a better predictor of GFR than creatinine clearance

Answer 22

Urea Clearance

Question 23

It has shown promise as a replacement for serum creatinine in estimation of GFR.

Answer 23

Cystatin C

Question 24

a measure of the amount of creatinine eliminated from the blood by the kidneys, and
GFR are used to gauge renal function

Answer 24

Creatinine Clearance