immunohema Flashcards
is the most important blood group system after ABO in transfusion medicine
RH
Individuals who lack D antigen DO NOT have anti-D.
TRUE
Immunogenicity of D greater than that of all other RBC antigens studied.
TRUE
Two of the terminologies are based on the
postulated genetic mechanisms of the Rh system.
3rd terminology describes only the
presence or absence of a given antigen
4th is result of the effort of
International Society of Blood Transfusion (ISBT) Working Party on Terminology for Red cell Surface antigens.
Suggested that antigens are determined by 3 closely linked sets of alleles.
Fisher-Race (CDE Terminology)
3 linked alleles
D or d (Presence or absence of the D antigen)
C or c (C and c antigens)
E or e (E and e antigens)
Postulated that TWO genes, one on each chromosome pair, controls the entire express of Rh system
2- Wiener (The Rh-Hr terminology)
Each gene produces a structure on the red cell called an
agglutinogen (antigen)