Amiodarone Flashcards

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1
Q

Amiodarone Class

A

Antidysrhythmin Class III

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2
Q

Amiodarone Action

A

Slows heart rate by prolonging the duration of the action potential and refractory periods; relaxes smooth muscles, causing vasodilation especially in coronary arteries; also has anti-anginal and sympatholytic properties

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3
Q

Amiodarone Indications

A

V-Fib, hemodynamically unstable V-Tach, SVT, a-fib, a-flutter, and junctional tachycardia; also used to treat non-exertional angina

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4
Q

Amiodarone Contraindications

A

Hypersensitivity, 2nd or 3rd degree heart block, sick sinus syndrome, bradycardia, cariogenic shock

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5
Q

Amiodarone Onset

A

Immediate

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6
Q

Amiodarone Durations

A

30-45 min

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7
Q

Amiodarone Adult dose - pulseless v-fib or v-tach (arrest):

A

300 mg IV/IO, then 150 mg in 3–5 minutes if needed

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8
Q

Amiodarone Adult dose - V-Tach with a pulse:

A

150 mg IVPB over 10 minutes (15 mg/min) repeated PRN or 360 mg over 6 hours (1 mg/min)

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9
Q

Amiodarone Adult dose - Maintenance infusion:

A

540 mg IVPB over 18 hours (0.5 mg/min) or 2.2 g IVPB over 24 hours

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10
Q

Amiodarone Pedi dose - pulseless v-fib or v-tach (arrest)

A

5 mg/kg IV/IO, repeated PRN (300 mg single dose max, 15 mg/kg total daily max)

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11
Q

Amiodarone Pedi dose - V-Tach with a pulse:

A

5 mg/kg over 20–60 minutes (15 mg/kg total daily max)

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12
Q

Amiodarone side effects

A

Headach, dizzyness, hypotension, CHF

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13
Q

Amiodarone interactions

A

Increases digoxin levels and enhances other ventricular antiarrhythmics, incompatible with sodium bircarbante, heparin and aminophylline

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14
Q

Amiodarone special considerations

A

Use caution in children and pts with goiter, hx or thyroid dysfunction, CHF, electrolyte

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