A/09

Question 1

What type of infarct is the cerebral infarct?

Answer 1

Liquefactive anemic

Question 2

Pathogenesis of cerebral infarct (3)

Answer 2

1/ AS occlusion of cerebral arteries
2/ Systemic embolism
3/ Venous (sinus) thrombosis - haemorrhagic

Question 3

Morphology of cerebral infarct (3)

Answer 3

1. Encephalomalacia alba
2. Encephalomalacia flava
3. Encephalomalacia rubra

Question 4

What is the difference with encephalomalacia rubra?

Answer 4

It is a haemorrhagic type of infarct

Question 5

What cells will be damaged first in the brain in hypoxia?

Answer 5

Neurons

Question 6

How long is the encephalomalacia alba?

Answer 6

First 48 hours

Question 7

Characteristics of encephalomalacia alba (2)

Answer 7

• necrotic area is swollen and soft

- macrophage infiltration by day 3

Question 8

Characteristics of encephalomalacia flava (2)

Answer 8

• liquefaction of infarct

- irregular small cavities

Question 9

What causes encephalomalacia rubra? (2)

Answer 9

• Venous obstruction (most likely thrombus)

- Reperfusion of anaemic infarct

Question 10

What is post encephalomalaciatic cyst?

Answer 10

Rim of gliosis around cyst, 1 month after infarct

Question 11

Encephalomalacia alba is usually in which matter

Answer 11

White matter

Question 12

Encephalomalacia rubra is usually present in which matter

Answer 12

In grey matter

Question 13

What is a hemorrhagic infarct?

Answer 13

Infarction is accompanied by bleeding

Question 14

What causes e. Flava?

Answer 14

Breakdown of lipid content