6.8.16 Flashcards
Turner synd: renal ssx
- horseshoe kidney
Turner synd: lymph ssx
- lymphedema
- cystic hygroma
Turner synd: cardiac ssx
- bicuspid aortic valve
- aortic coarctation
Turner synd: gyn ssx
- streak ovaries
- 1ary amenorrhea
- infertile
Turner Synd: physical appearance
- short stature
- web neck
- shield chest
- low post hairline
neural tube defect: prenatal dx
AFP & ACE in amniotic fluid
chronic renal allograft rejection: ssx
- worsening HTN
- slow progressive rise in serum Cr
chronic renal allograft rejection: renal bx findings
- obliterative fibrous intimal thickening
- tubular atrophy
- interstitial fibrosis
post triangle of neck: which N vulnerable to injury?
spinal access N (CN XI)
injure spinal access N: affect which muscle?
trapezius
weak trapezius: ssx
- shoulder droop
- impaired abduction of arm above horizontal
- winging of scapula
drugs w high hepatic clearance tend to have what property?
high lipophilic ==> & high vol of dist
geriatric pt: drugs to avoid
- antichol –> ie 1st gen antihist
- a-blocker
- TCA
- sulfonylurea
- sedating pain meds
what stimulates insulin release?
increased ATP production in pancreatic beta cell
maturity-onset diabetes of the young: cause
glucokinase mutation
Case: central vasc catheter + TPN + yeast in blood –> what infection?
candida
femoral N injury: ssx
- weak quadriceps
- loss of patellar reflex
- loss of sensation: ant/med thigh, medial leg
femoral N: runs along what muscle?
iliopsoas
what indicates severe mitral regurg?
S3 –> high regurg vol, LV vol overload
what produces S3?
tensing of chordae tendinae during rapid filling & expansion of ventricle
what is: metab by 1st order kinetics
constant fraction of drug eliminated per unit time
drug –> continuous infusion –> metab by 1st order kinetics: how long to reach steady state?
4-5 half lives
which histone is outside the histone core?
H1
RA: typical findings
PIP & MCP: bilat pain, stiff, deformity
what is: rheumatoid factor
IgM autoAb to Fc portion of IgG
rheumatoid factor: indicates
marker of tissue damage & dz activity
anaerobic glycolysis: how regenerate NAD+?
NADH transfer electrons to pyruvate to form lactate
why is it important to regenerate NAD+ in glycolysis?
G3P deH: glyceraldehyde-3-phosphate (G3P) –> 1-3-bisphosphoglycerate (BPG)
Cells have limited amts of NAD+ –> need for above run –> if use up NAD+ without regenerating it –> no more glycolysis
vitA def: ssx
- night blindness
- hyperkeratosis
vitA def: cause
- biliary disorder
- exocrine pancreas insuff
- intestinal malabsorption
skeletal muscle contraction cycle: ATP binding causes?
myosin head to detach from actin filament
