6.6.16

Question 1

manic episode: ssx

Answer 1

DIGFAST

• distractable
• impulsive/indiscrete
• grandiose
• flight of ideas
• activity increase
• sleep decrease
• talkative

Question 2

filtration fraction: calc

Answer 2

FF = GFR/RPF

Question 3

renal plasma flow: calc

Answer 3

RPF = RBF(1-hct)

Question 4

a-ketoglutarate deH: what rxn?

Answer 4

TCA: a-ketoglutarate –> succinyl CoA

Question 5

superficial inguinal ring: forms from

Answer 5

external oblique aponeurosis

Question 6

deep inguinal ring: forms from

Answer 6

transversalis fascia

Question 7

what is: pica

Answer 7

compulsive consume nonfood, non staple food source for >1mo

Question 8

pica: who?

Answer 8

• preg

- schoolchildren

Question 9

pica: assoc dz

Answer 9

nutritional def –> i.e. iron def anemia

Question 10

direct Coombs test: detects

Answer 10

Ab bound to RBC

• autoimmune hemolytic anemia

Question 11

indirect Coombs test: detects

Answer 11

RBC Ab in serum

• blood transfusion

Question 12

hemolytic dz of newborn (erythroblastosis fetalis): #1 cause

Answer 12

Rh incompatibility

Question 13

Rh incompatibility: fetal ssx

Answer 13

• severe autoimmune hemolytic anemia

- life-threatening hydrops fetalis

Question 14

supracondylar humeral fx: what may be injured?

Answer 14

• brachial A
• median N
• radial N

Question 15

supracondylar humeral fx –> proximal fragment –> lat displaced: what most likely injured?

Answer 15

radial N

Question 16

classic galactosemia: mode of inheritance, def

Answer 16

AR

galactose-1-phosphate uridyl transferase

Question 17

Lesch-Nyhan synd: mode of inheritance, def

Answer 17

XR

hypoxanthine-guanine phosphoribosyltransferase (HGPRT)

Question 18

homocystinuria: def

Answer 18

cystathionine synthase: homocysteine –> cysteine

Question 19

homocystinuria: ssx (4)

Answer 19

1) hypercoag –> thromboembolic occlusion –> premature ACS (homocysteine is prothrombotic)
2) ectopic lentil
3) MR
4) elevated methionine (homocysteine buildup)

Question 20

what aa becomes essential in homocystinuria?

Answer 20

cysteine

Question 21

TE fistula w esophageal atresia: clinical presentation

Answer 21

• excessive drooling

- choking, cyanosis during feeds

Question 22

fxal hypothalamic amenorrhea: pathophys

Answer 22

excessive wt loss, strenuous exercise, chronic illness, eating disorder –> decrease adipose –> decrease leptin –> hypo –> inh pulsatile GnRH release –> pit –> no LH, FSH –> low circulating estrogen –> amenorrhea

Question 23

optic tract lesion: leads to

Answer 23

contralat eye defect:

• homonymous hemianopia
• relative afferent pupillary defect (Marcus Gunn pupil)