6.23.16 Flashcards

1
Q

low C1 esterase inhibitor –> dx?

A

hereditary angioedema

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2
Q

3rd pharyngeal pouch: derivatives

A
  • thymus

- inf PTH gland

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3
Q

medullary thyroid CA: histology

A
  • nests/sheets of polygonal/spindle-shaped cells

- extracell amyloid deposits (calcitonin)

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4
Q

charact of UC

A
  • rectum always involved
  • inflamm limited to mucosa & submucosa only
  • mucosal damage is continuous
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5
Q

myasthenia gravis: assoc disorder

A

thymic abnormality –> thymoma, thymic hyperplasia

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6
Q

acute bacterial parotitis: how dx?

A
  • high amylase

- normal lipase (no evidence of pancreatitis)

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7
Q

bradykinin: fx

A
  • vasodilate

- increase vasc permeability

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8
Q

acute bacterial parotitis: RF

A

decreased salivary flow:

  • antichol
  • calculi
  • dehydrate
  • intubate
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9
Q

charact of Crohns

A
  • transmural inflamm
  • perianal fistula
  • noncaseating granuloma
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10
Q

acute bacterial parotitis: who?

A

elderly –> postop –> intubate, dehydrate

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11
Q

trochlear N palsy: how do pts compensate?

A

tuck chin, tilt head away from affected eye

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12
Q

the thymus arises from what embryologic struct?

A

3rd pharyngeal pouch

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13
Q

urge incontinence: tx

A

antimusc (M3)

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14
Q

C1 esterase inhibitor: fx

A
  • inh C1 activation –> no classic complement pathway

- inactivate kallikrein

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15
Q

trochlear N palsy: ssx

A

vertical diplopia –> worsen when look down & in (walk downstairs, up-close reading)

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16
Q

gluconeogenesis: what step utilizes GTP?

A

phosphoenolpyruvate carboxykinase (PEPCK): oxaloacetate –> PEP

17
Q

where will u find high levels of sorbitol deH?

A
  • seminal vesicles

- lens

18
Q

urge incontinence: pathophys

A

detrusor instability –> uninh bladder contract

19
Q

what mediates the angioedema in hereditary & acquired angioedema?

A

bradykinin

20
Q

what can cause angioedema?

A

ACEI

21
Q

cardiac catheterization –> where on common femoral A?

A

below inguinal lig

22
Q

TCA: what step generates GTP?

A

succinyl CoA synthetase: succinyl CoA –> succinate

23
Q

what naturally alleviates myocardial ischemia?

A

collateral circ –> blood to areas distal to occluded vessel

24
Q

femoral triangle: contains?

A

NAVEL (lat to med):

  • femoral N
  • femoral A
  • femoral V
  • deep inguinal nodes/lymph vessels
25
Q

acute bacterial parotitis: most common org

A

staph aureus

26
Q

how does ACEI cause angioedema?

A

normally: ACE –> bradykinin to inactive metabolites
ACEI: bradykinin accumulate

27
Q

strawberry hemangioma: natural progress

A

grow in proportion to child –> eventual regress –> completely by 7yo

28
Q

hereditary angioedema: what drug is contraindicated?

A

ACEI

29
Q

cardiac catheterization: what vessel?

A

common femoral A

30
Q

coronary steal: effect

A

hypoperfusion to ischemic areas

31
Q

what is sorbitol metab into? by what?

A

fructose

sorbitol deH

32
Q

if you access the common femoral A above the inguinal lig –> what can happen?

A

retroperitoneal hemorrhage

33
Q

what is: coronary steal

A

phenomenon in which blood flow to ischemic areas is reduced d/t arteriolar vasodilation in nonischemic areas

34
Q

trochlear N palsy: cause

A
  • idiopathic

- trauma

35
Q

what can cause coronary steal?

A

adenosine, dipyridamole –> coronary arteriolar vasodilate