6.23.16 Flashcards
low C1 esterase inhibitor –> dx?
hereditary angioedema
3rd pharyngeal pouch: derivatives
- thymus
- inf PTH gland
medullary thyroid CA: histology
- nests/sheets of polygonal/spindle-shaped cells
- extracell amyloid deposits (calcitonin)
charact of UC
- rectum always involved
- inflamm limited to mucosa & submucosa only
- mucosal damage is continuous
myasthenia gravis: assoc disorder
thymic abnormality –> thymoma, thymic hyperplasia
acute bacterial parotitis: how dx?
- high amylase
- normal lipase (no evidence of pancreatitis)
bradykinin: fx
- vasodilate
- increase vasc permeability
acute bacterial parotitis: RF
decreased salivary flow:
- antichol
- calculi
- dehydrate
- intubate
charact of Crohns
- transmural inflamm
- perianal fistula
- noncaseating granuloma
acute bacterial parotitis: who?
elderly –> postop –> intubate, dehydrate
trochlear N palsy: how do pts compensate?
tuck chin, tilt head away from affected eye
the thymus arises from what embryologic struct?
3rd pharyngeal pouch
urge incontinence: tx
antimusc (M3)
C1 esterase inhibitor: fx
- inh C1 activation –> no classic complement pathway
- inactivate kallikrein
trochlear N palsy: ssx
vertical diplopia –> worsen when look down & in (walk downstairs, up-close reading)
gluconeogenesis: what step utilizes GTP?
phosphoenolpyruvate carboxykinase (PEPCK): oxaloacetate –> PEP
where will u find high levels of sorbitol deH?
- seminal vesicles
- lens
urge incontinence: pathophys
detrusor instability –> uninh bladder contract
what mediates the angioedema in hereditary & acquired angioedema?
bradykinin
what can cause angioedema?
ACEI
cardiac catheterization –> where on common femoral A?
below inguinal lig
TCA: what step generates GTP?
succinyl CoA synthetase: succinyl CoA –> succinate
what naturally alleviates myocardial ischemia?
collateral circ –> blood to areas distal to occluded vessel
femoral triangle: contains?
NAVEL (lat to med):
- femoral N
- femoral A
- femoral V
- deep inguinal nodes/lymph vessels
acute bacterial parotitis: most common org
staph aureus
how does ACEI cause angioedema?
normally: ACE –> bradykinin to inactive metabolites
ACEI: bradykinin accumulate
strawberry hemangioma: natural progress
grow in proportion to child –> eventual regress –> completely by 7yo
hereditary angioedema: what drug is contraindicated?
ACEI
cardiac catheterization: what vessel?
common femoral A
coronary steal: effect
hypoperfusion to ischemic areas
what is sorbitol metab into? by what?
fructose
sorbitol deH
if you access the common femoral A above the inguinal lig –> what can happen?
retroperitoneal hemorrhage
what is: coronary steal
phenomenon in which blood flow to ischemic areas is reduced d/t arteriolar vasodilation in nonischemic areas
trochlear N palsy: cause
- idiopathic
- trauma
what can cause coronary steal?
adenosine, dipyridamole –> coronary arteriolar vasodilate
