4.9 Endocrine female Flashcards

1
Q

two cycles and main functions?

A

1) ovarian cycle = primary function is development and release of mature ovum
2) uterine cycle = primary function is preparation of uterin endometirum for implantation

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2
Q

4 parts of ovarian cycle

A

1) follicular growth phase
- -from primordial immture follciel to mature graadian follicle
2) ovulation
- -when follicle opens and releases mature egg (ovum)
3) luteal phase
- -what is left over after egg is released is cells ‘corpus luteum
4) involution
- -what happen to corpus luteum if there is no fertilization

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3
Q

follicular growth phase of ovarian cycle

A
  • before ovulation
  • lasts 14 days
  • primordial follicle into graafian follicle
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4
Q

ovulation of ovarian cycle

A
  • release mature ovum

- occurs on 14th day in middle of cycle

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5
Q

luteal phase of ovarian cycle

A
  • phase immediatley after ovulation
  • lasts 12 days
  • development of corpus luteam from follicle
  • corpus luteum secrete progesterone (And some estrogen)
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6
Q

involution of ovarian cycle

A
  • final phase of ovarian cycle
  • lasts 2 days
  • regression of corpus luteum into nonfunctional corpus albicans
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7
Q

what are the 3 phases of uterine cycle?

A

1) menstural phase
2) proliferation phase
3) secretoary phase

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8
Q

menstraul phase of uterine cycle

A
  • necrotic endometirum is sloughed off from PREVIOUS cycle if no fertilization happened
  • lasts an average of five days
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9
Q

proliferation phase of uterine cycle

A
  • regrowth of endometrium fro current cycle

- lasts 9 to 11 days

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10
Q

secretory phase of uterine cycle

A
  • endometrial glands secrete fluid and mucus for potential implanted blastocyst
  • lasts 12 days
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11
Q

6 important hormones for females?

A

1) estrogen
2) progesterone
3) follicle stimulatinghormone
4) luteinizing hormone
5) human chorionic gonadotropin
6) inhibin

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12
Q

what does estrogen primarily promote?

A

growth and proliferation of structural changes like endometrail proliferation, vascular growth, and framework of mammary glands

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13
Q

progesterone functions?

A

endometrial glandular secretions and alveolar development of mammary glands

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14
Q

FSH function?

A

1) follicle growth and devel

2) estrogen secretion from follicle

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15
Q

estrogen more important for?

progesterone more important for?

A
estrogen= follicular devel
progesterone= during corpus luteum
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16
Q

LH function?

A

1) ovulation
2) luteinization after ovulation and devel of CL
3) pregoesterone secretion from CL

17
Q

Why does LH keep CL alive?

A

so it can secrete progesterone until placenta is formed and can do it

18
Q

human chorionic gonadotropin (hCG) finction?

A

act like LH

  • luteinization and devel of CL
  • progesterone secretion from CL
19
Q

inhibin function

A

inhibits FSH production and secretion

20
Q

E and P negtive feedback on?

A

hypothalamus and Ant Pit

*estrogen better, both can do alone, together is best

21
Q

is E or P the framework or secretion?

A
E= framework
P= secretion
22
Q

why does E and P having similar structure to aldosterone matter?

A

bc aldosterone deals with water resorption

*If E and P are structurally similar they can retain Na, water and make you blaoted

23
Q

cause of menopause?

A

failure of follicle to respond to gonadotropins (LSH and LH still high, but no response!)

24
Q

menopause has incline of what hormones and decline of what hormone?

A

incline in gonadotropins

  • -decline in E and P
  • -ovulation stops
25
Q

hyper vs hypogonadism?

A
  • *hyper= too much estrogen causing thick endometrium and irregular heavy cycles due to tumor
  • *hypo= low estrogen due to poorlu developed ovaries causing childlike sexular development or greater than normal growth in heght bc late plate union and amenorrhea
26
Q

amenorrhea

A

prolonger menstrual cycles with long time between menstural phases

27
Q

E and P affect on uterus

A
E= irritant, avoid prego
P= calmer, best for implantation
28
Q

two drugs to increase fertility?

A

pergonol and clomid; both stimulate gonadotropin production (induce ovulation and follicular growth)

29
Q

define capacitation

A

enzymes from endometrium digest layer of glucoprotein off sperm so it can fertilize ovum

30
Q

what promotes sperm movement?

A

1) oxyocin from female
2) prostaglandin release from male and female
3) uterine and ductile contractions

31
Q

ferilization occurs in?

A

ampulla

32
Q

takes how long for 1st cell division?

A

30 hours

33
Q

morulla

A

at least 8 cell big ball

- takes 3 days

34
Q

blastocyst

A

hollowing of ball to become a blastocyst

  • takes 64 cells and 5-6 days
  • *WHAT EMBEDS INTO endometrium
35
Q

two parts of blastocyst?

A

1) trophoblast that becoems placenta

2) inner cell mass that becomes embryo

36
Q

implantation occurs?

A

6-7 days

37
Q

trophoblasts does what?

A

1) secrete enzymes and helps blastocyst implantation
* **syncytiotrophoblast
2) projection to contact vasculature
* **
sytotrophoblast

38
Q

prego test?

A

hCG blood and urine assays allow for early detection of pregonancy (8-10 days after ovulation)

39
Q

estrogen dual role?

A

1) myometrium irritant
2) increase # of oxytocine = INDIRECT AFFECT to promote making of oxytocine receptors on myometrium (cause contractions more easily in next prego)