2.9 Flashcards
what are examples of innate immunity to extracellular bacteria
- complement activation
- opsonization & phagocytosis
- stimulation of inflammatory reactions via anaphylatoxin
___ eliminate microbes and neutralize their toxins via antibodies that recognize cell wall antigens and secreted / cell-associated toxins
humoral immunity
humoral immunity involves Ig induced ___, ___, & ___
- opsonization
- phagocytosis
- complement activation
in cellular-mediated immunity to extracellular bacteria, bacterial protein antigens processed by DC activate ____
CD4 helper T cells
in cellular-mediated immunity to extracellular bacteria activation of helper cells leads to production of ___
- IL-17 & neutrophil recruitment
- IFN gamma & activation of macrophages
- B cell help
innate immunity involves ___ and ___ before cells become infected
phagocytes
complement
___ are activated directly or via IL-12 produced by macrophages
NK cells
what do CD4 T cells differentiate into
Th1 effectors via IL-12
___ occurs by T-cell derived signals (IFN gamma)
macrophage activation
___ of infected cells occurs by cytotoxic CD8 cells (CTL)
lysis
what increases the risk of oral candidiasis or thrush
wearing upper dentures or dry mouth
innate and adaptive immune responses block ___ and lead to ___
- block
- elimination of infected cells
innate immunity against viruses involves __ & __
- IFN alpha
- NK cell killing
what do antibodies involved in the immune response against viruses do
- neutralize virus
- activate complement
- lead to opsonization of viral particles
what kills viro- infected cells
CD8 T cells
