1.61 Brain Blood Supply Flashcards
What does the MCA supply?
Lateral surface of the brain and supplies temporal, parietal and frontal lobes of ipsilateral cerebral hemisphere
Lenticulostriate artery which supplies the basal ganglia - relevant with stroke
What does the choroidal artery supply?
It supplies the choroid plexus of the lateral ventricle, the optic tract, the internal capsule, medial parts of the basal ganglia, the medial parts of the temporal lobe, the thalamus, the lateral geniculate body, the proximal optic radiation and the midbrain.
What can a berry aneurism affect?
A small anureusims (berry aneurism) can alter the ability of the occulomotor nerve.
Occulomotor coming out between the superior cerebellar artery and posterior cerebral artery.
What is found in the centre of circle of wills?
Artrial connections found on the base of the midbrain encircling the pituatary glandm the mammillary bodies and optic nerves II
What would a blockage in the posterior cerebral artery cause?
blindness - supplies the visual cortex
What would a blockage in the anterior spinal artery result on?
lockage would cause loss of motor and pain and temp - but wouldn’t effect the dorsal columns - anterior lesion the ventral horns due to a blockage of anterior spinal artery
What would a blockage in the pontine/basilar arteries cause?
locked in syndrome - all the descending fibres running through the pons - cranial nerve nuclei - the only cranial nerve nucleus that would not be effected is the oculomotor nerve - someone still has cortical function but cannot communicate or express the movements except for eye movement by the oculomotor - up and down eye movements only
What would a middle cerebral stroke result in?
Middle cerebral stroke - take out motor and sensory predominantly head and arms - primary auditory cortex, however not seen because its bilateral - gustatory area
What would a lacunar stroke result in?
supply thalamus and posterior limb of our internal capsule - anterior; caudate nucleus and anterior limb of internal capsule - easily blocked
What do the perforating arteries supply?
deep into the caudate
Which type of capillaries are part of the blood brain barrier?
Type 1 capillaries
What else is part of the blood brain barrier?
Tight junctions between cells
Further protected by a cell membrane lining on their outer surface from adjacent glial cells, these create a thicker, more impermeable membrane.
Process - foot of astrocytes - tight junctions between those too. - important in maintaining the exact ion concentration - you have got to maintin a cosntant resting membrane potential.
What are circumventricular organs?
where the barrier is fault or does not exist - primarily found around the brin;s ventricular system - these include the pineal gland, the subcommissural organ, the area postrema, the subfornical organ, the organu, vasculosum, the median eminence and the posterior pituatary
When can the blood brain barriar be compromised?
comrpomised during inflammation, traumatic brain injury or stroke. - meningitis, epiplepsy, MS
What is the difference between grey and white matter blood flow?
Gray matter BF 6X greater than white matter BF
