1.103 Fracture repair Flashcards
Give an example of a fracture of compact bone?
Femoral shaft
What is cancellous bone?
Spongy bone - femoral metaphyses
What is a fracture in the immature (woven) bone called?
Fracture callus
What are Volkmann’s canals and where are they found?
Contain blood vessels in cortical bones (femoral shaft)
Which bone shave high and low turnover rate?
Crotical - low turnover
cancellous - spongy - high turnover
What is the bone matrix made up of?
Organic - 40% Collagen type 1 Proteoglycans Inorganic - 60% Calcium and phosphate type compounds
What is a basic multicellular unit?
Remodelling occurs via small packets of osteoblasts and osteoclasts
What is Wolf’s law?
Increased mechanical stress gains bone density
Fracture patients should weight bear
What are the stages of fracture healing?
Haemorrhage Inflammation Callus repair Callus consolidation Remodelling
What happens in the inflammation stage of fracture repair?
Acute inflammatory response Out pouring inflammatory exude Proteins Fibroblasts Hemapoeitic cells Growth factors Granulation tissue around fracture ends Immature osteoblasts
What is the purpose of inflammation?
Essential for bone repair
Removes dead tissues - macrophages
Enables correct cells to be recruited in the area
What is callus formation?
Immature bone - 2 weeks after fracture
Chondronergic and osteogenic cells proliferate
Thick cellular mass - Callus
This splints the bone ends
Osteoclasts absorb and mop up damage done
What is callus consolidation?
Immature (callus) bone transformed into mature - lamellar - bone
What is a stress fracture?
abnormal repetetive stress
What is a fatigue fracture?
repetetive stress on an abnormal bone - osteoporosis