14 Lymphatic and Immune System Pathology

Question 1

sever combined immunodeficiency disease (SCID)

Answer 1

infants born with a deficiency of B and T cells, lack of immunity

Question 2

acquired immunodeficiency syndrome (AIDS)

Answer 2

group of clinical s/s associated with supression of immunity and marked by opportunistic infections, secondary neoplasms, and neurologic problems

Question 3

AIDS cause

Answer 3

human immunodeficiency virus (HIV), destroys helper T cells (CD4) disrupts immunity allowing infection to occur

Question 4

Opportunistic infections with AIDS

Answer 4

candidiasis, Crypto, herpes simplex, Histo, PCP, Toxo, TB

Question 5

Malignancies associated with AIDS

Answer 5

Kaposi sarcoma- cancer arising from lining of cells and capillaries (purple lesions), lymphoma (cancer of lymph nodes) and wasting syndrome

Question 6

s/s of HIV

Answer 6

lymphadenopathy, neurologic disease, oral thrush, night sweats, fatigue, and evidence of opportunistic infection

Question 7

allergy

Answer 7

abnormal hypersensitivity acquired by exposure to antigen

Question 8

lymphoma

Answer 8

malignant tumor of lymph nodes and lymph tissue. Hodgkin disease, Non-hodgkin

Question 9

Hodgkin disease

Answer 9

spleen and lymph nodes, lymphadenopathy (enlarged nodes) splenomegaly, fever, weakness, loss of weight and appetite. Identify Reed-Sternberg cell

Question 10

Non-Hodgkin lymphomas

Answer 10

follicular and large cell lymphoma. mostly b cell lymphomas and rarely T cell malignancies

Question 11

multiple myeloma

Answer 11

malignant tumor of bone marrow cells, composed of plasma cells

Question 12

thymoma

Answer 12

malignant tumor of the thymus gland

Question 13

protease inhibitor

Answer 13

drug that treats AIDs by blocking reverse transcriptase, and enzyme needed to make copies of HIV