Wernickes + Korsacoff's Flashcards
1
Q
What is the cause of Wernicke’s
A
Thiamine deficiency mostly seen in alcoholics
2
Q
Classic triad of Wernickes
A
Ophthalmoplegia/ nystagmus, ataxia, encephalopathy
3
Q
Features of Wernicke’s encephalopathy
A
Oculomotor dysfunction, gait ataxia, confusion, disorientation, indifference, inattentiveness, peripheral sensory neuropathy
4
Q
Investigations into Wernickes
A
Decreased red cell transketolase, MRI
5
Q
Management of Wernickes
A
Urgent replacement of thiamine
6
Q
What is Korsakoff’s syndrome
A
Marked memory disorder, from thiamine deficiency causing damage and haemorrhage to mammillary bodies to hypothalamus and medial thalamus
7
Q
Features of Korsakoff’s syndrome
A
Anterograde amnesia, retrograde amnesia, confabulation
