Neuroleptic Malignant Syndrome Flashcards
1
Q
Cause of NMS
A
Antipsychotic medication, but also can occur with dopaminergic drugs
2
Q
When does NMS occur
A
Hours to days of starting an antipsychotic
3
Q
Features of NMS
A
Pyrexia, muscle rigidity, hypertension, tachycardia and tachypnoea, agitated, delirium, confusion
4
Q
What might blood results show in NMS
A
A raised creatine kinase, AKI might develop in severe cases, leukocytosis may also be seen.
5
Q
Management of NMS
A
Stop antipsychotic, IV fluids to prevent renal failure, dantrolene useful in selected cases
