HHS Flashcards
1
Q
Pathophysiology of HHS
A
Hyperglycaemia -> increased serum osmolality -> osmotic diuresis -> severe volume depletion
2
Q
Precipitating factors for HHS
A
Intercurrent illness, dementia, sedative drugs
3
Q
Clinical features of HHS
A
Over many days, there may be polyuria, polydipsia, signs of dehydration, lethargy, nausea and vomiting, altered conscioussess, focal neurological deficits, hyperviscosity
4
Q
Typically findings in HHS
A
Hypovolaemia, >30 glucose, raised serum osmolality (>320), no significant hyperketonaemia or acidosis
5
Q
Management of HHS
A
Fluid replacement, typically 0.5-1l/ hr, insulin not given unless blood glucose stops falling whilst giving IV fluids, VTE prophylaxis
6
Q
Complications of HHS
A
MI or stroke from hyperviscosity
