DIC Flashcards
1
Q
What is DIC
A
Inappropriate activation of the clotting cascade, resulting in thrombus formation and depletion of clotting factors and platelets
2
Q
Features of DIC
A
Excess bleeding, also may present with fever, confusion or coma, often in context of severe systemic disease..
3
Q
Physical signs of DIC
A
Petechiae, bruising, confusion and hypotension
4
Q
Risk factors for DIC
A
Major trauma or burns, multi-organ failure, severe sepsis of infecion, severe obstetric complications, solid tumours or haematological malignancies
5
Q
What subtype of leukaemia is associated with DIC
A
Acute promyelocytic leukaemia
6
Q
Investigation findings into DIC
A
Thrombocytopenia, increased prothrombin time, increased fibrin degradation products, decreased fibrinogen
