Week 7: Chapter 27 and Chapter 28 Study Guide Flashcards
Trade name: fluoxetine
Prozac
Trade name: lithium carbonate
Listhonate
Trade name: trazodone
Desyrel
Trade name: paroxetine
Paxil
Trade name: thiothixene
Navane
Trade name: clonazepam
Klonopin
Trade name: duloxetine
Cymbalta
Trade name: citalopram
Celexa
Trade name: escitalopram
Lexapro
Trade name: risperidone
Risperdal
Trade name: diazepam
Valium
Trade name: alprazolam
Xanax
A selective serotonin reuptake inhibitor blocks the reuptake of _______________, making it more available to act on ______________ in the brain.
Serotonin
Receptors
Tricyclic antidepressants act by blocking the reuptake of ____________ and __________, making more of these substances available to act on receptors in the brain.
Norepinephrine
Serotonin
Other terms for antipsychotic drug are _____________ _______________, and ______________.
major tranquilizers
neuroleptics
Another term for an antianxiety drug is _________________.
Anxiolytic
Neuroleptic malignant syndrome is associated with ____________________ temperature, __________________ pulse, __________________, _______________ respiratory rate, and ________________ or ______________ blood pressure.
elevated elevated elevated elevated decreased
Anxiety:
Feeling of dread about perceived danger or threat
Bipolar D/o
Alternating episodes of mania and depression
Depression:
Feelings of sadness, despair, loss of energy, and difficulty coping
Delusions:
Fixed false beliefs or opinions that are resistant to reason
Dysthymia:
Persistently low moods; less severe than depression
Hallucinations:
Sensory perceptions not actually present
Illusions:
Incorrect mental representations of misinterpreted events
Major depression:
Persistent low mood and lack of pleasure in life with an increased risk of suicide
Mania:
Extremely elevated mood with mental and physical hyperactivity
OCD:
Obsessive thoughts and compulsive actions
Panic disorders:
Unexpected attacks of anxiety or terror lasting 15 - 30 minutes
PTSD:
Anxiety D/O caused by serious traumatic events
Patient is taking venlafaxine, duloxetine, or bupropion are at risk for ________________.
Seizures
PTs on mitrazapine are at increased risk for infection because of:
Neutropenia
Because of their abuse potential, _________________ drugs are contraindicated for pts with a substance abuse D/O.
Benzodiazepines
Pts taking quetiapine may experience an alteration in _____________________ ____________________ ______________________.
Body Temperature Regulation
A pt who has been taking the benzodiazepine chlordiazepoxide (Librium) for anxiety reports after 2 weeks of therapy that she is feeling much calmer. This is a result of the enhanced inhibitory effects of which neurotransmitter?
Gamma-aminobutyric acid
A pt who have prescribed lorazepam (Ativan) for 2 months suddenly stopped taking it because she felt so much better. Now she reports restlessness, weakness, and insomnia. You should instruct her to call the prescriber and make an appointment immediately because of what risk associated with benzodiazepine withdrawl?
Seizures
A pt who is in her second trimester of pregnancy is experiencing emotional difficulty at home and asks her HCP for a prescription for lorazepam (Ativan) to help her cope. Why is this drug contraindicated for this pt?
The fetus can become dependent on the drug
A pt who has been taking sertraline (Zoloft) daily for 10 days reports that the medication has not helped with anxiety. What should the nurse tell the pt?
You must give the drug time because it usually takes several weeks to be effective
A pt who has begun treatment with 25 mg of chlorpromazine (Thorazine) BID. You should instruct the pt to be sure to practice which precaution?
Change positions and get up slowly
A pt has recently begun taking citalopram (Celexa) for symptoms of depression. You should monitor the pt for which common S/E?
- Insomnia
- Anorexia
- Increased sweating
A group of individuals is participating in a support session to help with depression. Which pt statement would warrant an immediate notification of his or her health care provider?
“If things don’t improve I’ll have no reason to live anymore”
A pt who has taken chlorpromazine (Thorazine) has developed symptoms of muscle rigidity, elevated temperature, increased RR, and elevated pulse and BP. In addition, the pt has become less responsive to verbal stimuli. Which A/E has this pt developed?
Neuroleptic malignant syndrome
Before giving clozapine (Clozaril) to a pt, you assess th pts smoking history. What is the reason for this assessment?
Smoking may decrease the effectiveness of clozapine
Which statement made by a pt best indicated that the pt correctly understands that correct use of olanzapine (Zyprexa)?
“I won’t take this drug with grape fruit juice to avoid excessive blood levels”
An older adult has been taking lithium and develops nausea and vomiting. Which intervention is most appropriate?
Contact the prescriber for possible parenteral fluids
A class of nonbenzodiazepine sedative hypnotics that interacts with the same receptor side that benzodiazepine drugs do, turning on the receptors that induce sleep:
Benzodiazepine receptor agonists
Drugs that promote sleep by targeting signals in the brain to produce calm and ease agitation
Sedatives
A class of drugs that depress the CNS by binding to GABA receptors resulting in hypnotic and sedating effects; they are used mainly to control symptoms of anxiety or stress
Benzodiazepines
Drugs used to treat allergies and allergic reactions. Some, such as diphenhydramine (Allerdryl/ Benadryl) and dimenhydrinate (Dramamine / Gravol) have sedating effects and are available OTC:
Antihistamines
A class of drugs formed from barbituric acid that induces sedation and general depression over all CNS function:
Barbiturates
Trade name: Lunesta
eszopiclone
Trade name: Dalmane
flurazepam
Trade name: ProSom
estazolam
Trade name: Restoril
temazepam
Trade name: Ambien
zolpidem
Trade name: Sonata
zaleplon
Trade name: Seconal
secobarbial
Benzodiazepines depress the CNS by binding to ________________ _____________.
GABA receptors
_________________ induce general depression over all CNS functions.
Barbiturates
_______________ and _______________ function are inhibited by barbiturates.
Motor
Sensory
Antihistamines produce __________________ and ___________________ ___________________.
Drowsiness
Mild sedation
Drugs for insomnia are metabolized by the ___________________ and excreted by the _________________.
Liver
Kidney
A pt taking eszopiclone should be warned that serious A/E of this drug are ______________ and ___________ ___________.
Sleepwalking
Sleep driving
A pt with reduced liver function who is taking a drug to treat insomnia may have a(n) ________________ drug level.
Higher
A pt has taken and overdose of benzodiazepine. What is the reversal agent? __________________. How is it administered? __________________.
romazicon (Flumazenil)
IV
Romazicon (Flumazeril) should not be given to a pt who has a(n) __________________ _________________.
Seizure D/O
Benzodiazepines are prescribed for a short term treatment for which reason?
They are habit forming
In addition to treatment for insomnia, barbiturates are used in management of which condition?
Epilepsy
Which intervention is most appropriate when administering a medication to treat insomnia?
Remind the pt to change positions slowly
A pt is taking a benzodiazepine receptor agonist for the first time at home. Which is the most appropriate instruction to give?
Have another person stay with you the first time you take this.
A pt requests information about taking zolpidem during an overnight airplane flight that lasts 5-6 hours. What information should the nurse provide?
This may cause a transient memory loss
A pt has had an overdoese of benzodiazepine. In addition to treatment with the reversal agent, the pt will need continued monitoring for which A/E?
Respiratory depression
Which considerations apply to an older adult who is taking a drug to treat insomnia?
Safety precautions are necessary to prevent falls
A mother who is breastfeeding an infant requests information on drugs to treat insomnia. Which information is most appropriate to provide?
The breastfed infant could be sedated by the medication
A pt will be taking flurazepam 30 mg this evening. The pt should monitored for which of the following S/E?
Daytime drowsiness
Blurred vision
Confusion