Week 7: Chapter 20 Flashcards

Drugs That Effect Blood Clotting

1
Q

What is the main purpose of anticoagulation?

A

To prevent clots from forming where they are not needed

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2
Q

Which condition is a common indication for the use of an anticoagulant drug?

A

Atrial fibrillation

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3
Q

Which of the following drugs or supplements makes the risk for bleeding worse when a patient is also taking an anticoagulant drug?

A
  1. Aspirin
  2. Gingko biloba
  3. St. John’s Wort
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4
Q

What agent is used as an antidote for a warfarin (Coumadin) overdose?

A

Vitamin K

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5
Q

Which action is essential before beginning continuous IV heparin therapy?

A

Get an accurate baseline patient weight

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6
Q

Which anticoagulant drug must be avoided during pregnancy because it can cause birth defects in the fetus?

A

Warfarin (Coumadin)

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7
Q

Which lab test result indicates that an antiplatelet drug is effective?

A

International Normalized Ratio (INR) is increasing

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8
Q

What agent is used as an antidote for a heparin overdose?

A

Protamine sulfate

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9
Q

After bleeding, what is the most common A/E of most antiplatelet drugs?

A

Decreased platelet count

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10
Q

Which action is important to prevent to prevent losing any part of the drug dose when administering low molecular weight heparin?

A

Not expelling the air bubble before injecting the drug

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11
Q

Why is the antiplatelet effect of aspirin longer lasting than that of other NSAIDs?

A

Aspirin irreversibly inhibits the production of TXA2, whereas NSAIDs cause reversible inhibition of this substance

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12
Q

Why is it important to teach the patient starting on the anticoagulant warfarin (Coumadin) to limit his/her intake of leafy green vegetables?

A

These foods contain vitamin K, which can reduce the effects of warfarin

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13
Q

What is the major MOA that allows thrombolytic drugs to dissolve clots?

A

Increasing the blood level of the enzyme plasmin

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14
Q

Which problems, conditions, or drugs are absolute contraindications for thrombolytic therapy?

A
  1. Recent head trauma

2. Undergoing cancer chemotherapy

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15
Q

What is the intended response when a patient is prescribed epoetin alfa (Epogen)?

A

RBC levels normalize

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16
Q

What instructions are important to give a patient who is on anticoagulant therapy? (select all that apply)

A
  1. Avoid contact sports
  2. Report headaches that will not go away
  3. Watch for S/S of bleeding
17
Q

The nurse is caring for a patient admitted after a thrombolytic event. What patient is most at risk for this type of event?

A

Bedridden patient

18
Q

The nurse is going to start anticoagulant drug therapy on a patient. Which patient conditions or histories would prohibit this therapy to be given to the patient? (select all that apply)

A
  1. Bleeding ulcer
  2. Recent stroke (within 2 months)
  3. Recent spinal surgery
  4. Delivery of a baby within the past 24 hrs.
19
Q

The nurse is performing an admission assessment on a patient admitted for thrombolytic therapy. The nurse knows that which condition is an absolute contraindication for thrombolytic therapy?

A

Recent delivery of a baby

20
Q

The nurse is caring for a patient receiving heparin therapy. Besides an increased risk for bleeding, what are other side effects you should be aware of for patients receiving this therapy?

A
  1. Decreased platelet count
  2. Hair loss
  3. Bone thinning
21
Q

The nurse is monitoring a patient who is receiving high-dose heparin therapy. What antidote must the nurse be sure is readily available?

A

Protamine sulfate

22
Q

At what times might anticoagulant drugs be prescribed? (select all that apply)

A
  1. After heart valve replacement
  2. For the dysrhythmia atrial fibrillation
  3. To prevent venous thromboembolism
  4. If a patient is at risk for a stroke
23
Q

The nurse is instructing a patient being discharged on anticoagulant drugs about possible signs of bleeding. What symptoms should the nurse tell the patient to look for? (select all that apply)

A
  1. Coffee ground emesis
  2. Abdominal pain
  3. Back pain
24
Q

The prescriber has ordered low-molecular-weight (LMW) heparin to be given to a patient. How is this drug administered?

A

Subcutaneously

25
Q

The nurse is caring for a patient who is going to be started on IV heparin. What factor determines the initial intravenous (IV) bolus dose for this patient?

A

Weight

26
Q

The nurse is caring for a patient on embolytic therapy. What possible adverse effects of aspirin therapy should the nurse make sure the patient understands? (select all that apply)

A
  1. Check for headaches or any changes in level of consciousness (LOC).
  2. Monitor for bleeding at least every 2 hours.
  3. Ensure all follow-up laboratory work for coagulations is completed.
27
Q

A patient is being sent home with instructions to take aspirin daily. The nurse needs to tell the patient what possible adverse effects of aspirin therapy? (select all that apply)

A
  1. Hemorrhage
  2. Salicylate poisoning
  3. Salicylate poisoning
28
Q

During pregnancy, a woman requires anticoagulation therapy. Which drug is likely to be prescribed?

A

Enoxaparin (Lovenox) or heparin

29
Q

A patient who has had a heart valve replacement takes warfarin (Coumadin) daily. The patient would require additional teaching if he or she selected which food items for lunch?

A

Spinach salad with bacon

30
Q

The nurse has an order to administer a thrombopoiesis-stimulating agent oprelvekin (Neumega). How should this medication be administered?

A

Subcutaneously (SQ)

31
Q

A patient who is taking warfarin (Coumadin) has an international normalized ratio (INR) of 1.0. What change in the warfarin dosage, if any, would the nurse expect?

A

The dose will increase.

32
Q

The nurse is caring for a patient who has been diagnosed with coronary artery disease. What is the most common antiplatelet drug the nurse would expect to see ordered for this patient?

A

Aspirin (Ecotrin)