Vit B12 deficiency

Question 1

Vitamin B12 deficiency

Answer 1

• affects both corticospinal tract and dorsal columns*; also affects *cerebellum

Question 2

• Symptoms of*
• Vit B12 deficiency*

Answer 2

• -paraesthesia*, bilateral weakness
• -Babinski sign*, ataxia (both motor and sensory or dorsal columns and lateral corticospinal tracts)
• Vit B12 deficiency = lesion of ascending dorsal column tract = (+) Romberg sign
• macrocytic anaemia

Question 3

Diagnosis of

Vit B12 deficiency

Answer 3

• ↑homocysteine*
• methylmalonate in serum*

Question 4

Symptoms of Vit B12 deficiency

in cerebellar syndrome with (-) Romberg sign
has

Answer 4

(intact proprioception and vestibular function)

Question 5

Vit B12 deficiency

Answer 5

-positive Babinski test whereas cerebellar syndrome is negative

• -with sensory deficiency*
• -Proprioception*