Early and Late post-traumatic brain lesions

Question 1

Early and late post-traumatic brain lesions

Early:

Answer 1

• • Early*
• occurs at the moment of injury, mechanically-induced - 2 mechanisms: contact, acceleration-deceleration

- eg. haematomas, haemorrhage, contusion, laceration, oedema

Question 2

Early and late post-traumatic brain lesions

Late:

Answer 2

Late

• *-** a result of process initiated by the trauma
• *-** ↑ICP –> ↓blood flow to brain –> cerebral hypoxia, ischaemia, oedema, hydrocephalus, herniation
• *-** ↑release of neurotransmiters (glutamate and aspartate) –> excitotoxicity
• *-** inflammatory response and free radical dammage

–> breakdown of BBB

Question 3

Early and late post-traumatic brain lesions

Focal vs diffuse

Answer 3

Focal - (Epidural, Subdural, Subarachnoid, Intraventricular, and Intracelebral) hemorrhage, and Cerebral contusion or lacerateion,

Diffuse- Diffused axonal Injury