Epilepsy Flashcards

1
Q

Epilepsy

Define:

A
  • chronic CNS disorders characterised by recurrent seizures
  • epileptic seizures are due to abnormal brain activity (confirmed on EEG) unattributable to organic causes
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2
Q

Define:

Epileptic seizure:

Epilepsy:

Epilepsy syndrome:

A
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3
Q

Epilepsy

2 major types:

A

Focal and General

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4
Q

Partial/Focal Seizure

A
  • Conscious (aura) or Unconscious*
    • Simple: sudden jerking, sensory phenomena*
    • Complex: simple partial seizures + impaired consciousness*
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5
Q

General Epilepsy

Examples: 6

A

Tonic-Clonic

Absence

Clonic

Tonic

Atonic

Myoclonic

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6
Q

Tonic Seizure

A
  • muscles stiffen
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7
Q

Clonic Seizure

A
  • rhythmic jerks of*
  • limbs, body, head*
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8
Q

Absence Seizure

A
    • brief loss and return of consciousness*
  • (aka Petit mal seizures)*
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9
Q

Myoclonic Seizure

A

- involve spasms of muscles

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10
Q

Atonic Seizure

A
    • loss of muscle activity for greater than one second*
  • (commonly seen as “head drop”)*
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11
Q

Tonic-Clonic Seizure

A

Tonic-Clonic

(aka Grand mal seizures)

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12
Q

Postictal state

A
  • altered state of consciousness after an epileptic seizure*
  • (drowsiness, confusion, headache)*
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13
Q

Todd’s paralysis

A

focal weakness in a part of the body

after a seizure

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14
Q

Trigger:

A

Trauma, Stress, drug withdraw, infection, electrolytic disturbances, hormone, alcohol, intense light, loss of sleep

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15
Q

What to do for a patient during a seizure

A

During episode patient’s mouth should be kept open, and his/her head should be hold to minimize damage.

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16
Q
  • Sign/Symptoms:*
  • of Seizure*
A

loss of memory, injury, sleepy,

Todd’s paralyses (neurologic deficit following a seizure that can last 24 hr), pee on pant

17
Q
  • Diagnosis-Tests for Epilepsy*
  • Name:*
A

EEG (see “spikes”)

Video EEG (to differentiate from pseudooseizure)

CT (to rule out tumour)

18
Q

Tx:

Partial

A

Partial

– Carbamazepine, Lamotrigine, Levetiracetam, Valproate

19
Q

Tx:

Generalised

A
  • Generalised

Carbamazepine, Valproate

20
Q

TX:

Absence **

A

Absence

1st line is

Ethosuximide

then Valproate​

21
Q

Tx:

Localized

A

Localized

carbamazepine, Phenytoin, Valproate, Lamotrigine

22
Q

Tx:

Myoclonic

A

Myoclonic

Valproic acid

23
Q

Tx:

Tonic-clonic

A

Tonic-clonic

Valproate, Lamotrigene