Vasculitis Flashcards
1
Q
What are large vessel vasculitis
A
Giant cell arteritis
Takayasu’s arteritis
2
Q
Takayasu’s arteritis criteria
A
3/6 required age < 40 claudication decreased brachial artery pulse BP diff > 10 mmHg between arms Bruit over subclav or aorta Anteriogram abnormatlity
3
Q
What are medium vessel vasculitis
A
polyarteritis nodosa
kawasaki’s dx
4
Q
Polyarteritis Nodosa criteria
A
3/10 required weight loss > 4 kg livedo reticularis testicular pain/tenderness myalgias, weakness, leg tenderness mono or polyneuropathy diastolic BP > 90 Elevated BUN/creatinine Hep B Arteriographic abnormality biopsy with PAN
5
Q
what are small vessel vasculitis
A
ANCA -wegners - churg strauss - microscopic polyangitis Not ANCA - henoch-schonlein purpura - cryoglobulinemia - 2/2 to CTD/RA
6
Q
What are ANCA
A
anti-neutrophil cytoplasmic antibodies
P-ANCA and c-ANCA used for Wegners
7
Q
Churg-strauss criteria
A
4/6 required Asthma Eosinophilia >10% WBC mono or polyneuropathy transitory pulmonary infiltrates paranasal sinus abnormality biopsy with eosinophils
8
Q
wegener’s criteria
A
2/4 required nasal/oral inflammation ab chest radiograph urinary sediment granulomatous inflammation on biopsy
9
Q
henoch-scholein purpura criteria
A
2/4 required palpable purpura age <20 bowel angina granulocytes in walls on biopsy
10
Q
vasculitis txt
A
steroids
bad but cytotoxic drugs
