Bone forming tumors

Question 1

What is Paget’s ds

Answer 1

old, bone enlarged

Question 2

What is fibrous dysplasia

Answer 2

young, bone enlarged

Question 3

What is osteopetrosis

Answer 3

Marble bone, no marrow space

Question 4

What is melorheostosis

Answer 4

Candlewax

Question 5

What is osteoma

Answer 5

Bone island, cancellous, pelvis

Question 6

Clinical signs of osteoid osteoma

Answer 6

Night pain, NSAIDs help
younger pt
Round nidus, metaphyseal cortex
Will resolve on own in up to 3 years

Question 7

What is important about osteosarcoma

Answer 7

High grade malignant bone forming tumor
occurs in teens and older adults
minimal sx, pts aren’t sick
Most die from metastasis to lungs

Question 8

What do you see on xray of osteosarcoma

Answer 8

Eats away at bone (lytic)
No sclerotic rim because bone doesn’t have time to form around it
Lucent areas aren’t yet calcified
“sunburst” appearance

Question 9

tx of osteosarcoma

Answer 9

1. staging workup (CXR, bone scan, etc)
2. CT guided core needle bx
3. pathology staging
4. pre op chemo
5. wide resection
6. post op chemo
7. surveillance (alk phos)
   NO RADIATION

Question 10

What is the MC benign cartilage lesion

Answer 10

Osteochondroma

Question 11

How do osteochondromas form

Answer 11

Grow from growth plates, point away from a joint

Question 12

Osteochondroma on xray

Answer 12

No periosteal rxn
continuity of stalk with canal
at growth plate
points away from joint

Question 13

What is an enchondroma

Answer 13

Begins in epiphysis, may calcify later in life

Question 14

What is the second MC malignant tumor of bone

Answer 14

Chondrosarcoma

Question 15

Do chondrosarcomas metastasize

Answer 15

Never metastisize but may recur

Question 16

Chondrosarcoma on xray

Answer 16

enchondroma
metaphyseal, diaphyseal
intra-medullary
lytic lesion
poorly marginated
looks like little bites are taken out of bone

Question 17

What is a UBC (unicameral bone cyst)

Answer 17

developmental defect with no bone at growth pate

Question 18

What is ABC (aneurysmal bone cyst)

Answer 18

cortex destroyed by periosteal rxn and bone balloons out

Question 19

Important notes about chondroblastoma

Answer 19

Occurs in teens and 20s
Always very painful
almost always in epiphysis and knee