Lupus Flashcards
1
Q
What is systemic lupus erythematosus
A
chronic autoimmune unknown etiology protein presentation multiple organ involvement autoantibody and immune complex production
2
Q
Who is more likely to get SLE
A
F
AA/Asians
3
Q
What is are tests for SLE
A
ANA (FANA)
ds-DNA
aPTT
4
Q
What type of raynaud’s is seen in SLE
A
Secondary
5
Q
What are criteria for SLE
A
4/11 required
- malar rash
- discoid rash
- photosensitivity
- oral ulcers
- arthritis
- serositis
- nephritis
- neurologic disorder
- hematologic disorder
- positive ANA
- Other positive (smith, DNA, antiphospholid)
6
Q
What is disoid lupus
A
cutaneous macules on skin
7
Q
What is commonly seen with SLE but not a criteria
A
alopecia
8
Q
What are musculoskeletal manifestations with SLE
A
arthralgias
myalgias
fibromyalgia
inflammatory polyarthritis
9
Q
What are renal manisfestations with SLE
A
renal failure
death
10
Q
what are neuropsychiatic manifestations with SLE
A
seizures psychosis cognitive deficits depression strokes HA aseptic meningitis
11
Q
What are cariopulmonary manifestations with SLE
A
Serositis
cariomyopathy
marantic endocarditis
12
Q
What are hematologic manifestations with SLE
A
anemia leukopenia lymphopenia thrombocytopenia thrombosis
13
Q
What is SLE txt
A
NSAIDs = muscleskeletal sun protection prednisone steroid sparing agents - hydroxychloroquine - azathioprine - MTX
