Inflammatory Myopathies Flashcards
1
Q
What are inflammatory myopathies
A
Adult Polymyositis (PM) Adult Dermatomyositis (DM)
2
Q
What epidemiology inflammatory myopathies
A
muscle weakness bimodal (10-15, 45-60) female more painless proximal & distal weakness Inclusion body myositis
3
Q
What are manifestations of inflammatory myopathies
A
elevated muscle enzymes (CPK) dysphagia ILD arthralgias Raynaud's skin manifestations
4
Q
What are skin manifestations of DM
A
Heliotrope rash
Shawl or V sign
Mechanic’s hands
gottron’s papules
5
Q
What are gottron’s papules
A
inflammation of MCP & PIP joints
6
Q
What is Inflammatory myopathies dgx
A
PM: 4/5
DM: 2/4
- Proximal m. weakness
- elevated m. enzymes
- myopathic changes on EMG
- Muscle biopsy
- skin rash
7
Q
What is inflammatory myopathies txt
A
glucocorticoids
CPK
steroid sparing agents
PT
8
Q
What is dgx for mixed CTD
A
U1-RNP antibody
puffy hands
