UWorld_7.25 Flashcards

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1
Q

Secondary causes of gout

A
  • hematologic malignancies
  • tumor lysis syndrome
  • psoriasis
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2
Q

Sx of polycythemia vera

A
  • H/A
  • aquagenic pruritus
  • HSM
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3
Q

Ventilation =

A

TV * RR

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4
Q

Heart defects assoc. w/Digeorge

A
  • cyanotic heart defects:
  • truncus art.
  • transposition
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5
Q

Cause of death in FA

A

cardiomyopathy

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6
Q

Gonococcal septic arthritis presentation

A
  • asymmetric polyarthralgias or isolate purulent mono/oligo arthralgias
  • assoc. w/skin rash and tenosynovitis
  • young, sexually active
  • most silent (no preceding infection)
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7
Q

Reactive arthritis presentation

A
  • assoc. w/chlamydia or GI infections
  • arthritis
  • conjunctivitis
  • urethritis
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8
Q

Vaccines in chronic liver disease

A
  • Hep A/Hep B
  • flu
  • Tdap q10 yrs.
  • PCV23 followed by normal pneumococcoal @ 65
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9
Q

Dx of myasthenia gravis

A
  • edrophonium (tensilon) test
  • ice pack test ==> improvement in weakness
  • Ach receptor antibodies
  • CT for thymoma eval
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10
Q

Enuresis age cut-off and tx

A
  • incontinence > 5yo

- 1st line = desmopressin; 2nd line: TCAs (impramine, amitriptyline)

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11
Q

Sodium bicarb use in metabolic acidosis

A

@ pH

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12
Q

isoniazid SE

A
  • pyridoxine (B6) antagonist

- supplement w/B6 during tx

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13
Q

Sideroblastic anemia presentation

A

-microcytic/hypochromic + elevated iron and decreased TIBC

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14
Q

elevated alk phos + anti-mitochondrial ab + ==> dx?

A

primary biliary cholangitis

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15
Q

Tx of primary biliary cholangitis

A

ursodeoxycholic acid

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16
Q

Neuro status in clinical brain death

A
  • absent cortical and brain stem fxns

- spinal cord may be fxning, DTRs present

17
Q

Legg-Calve-Perthes disease

A
  • idiopathic avascular necrosis of femoral capital epiphysis

- boys ages 4-10

18
Q

Tx of cryptococcal meningoencephalitis

A
  • amphotericin B + flucytosine IV x 2wks
  • then fluconazole x 1 yr.
  • serial LPs to reduce ICP if needed
19
Q

cryptococcal meningoencephalitis presentation

A
  • subacute fungal infection

- HIV w/CD4

20
Q

Statin MOA

A
  • imhibit HMG-CoA reductase

- inhibits intracellular synthesis of LDL receptors ==> decreased receptors @ cell membranes

21
Q

Imaging in eval of aortic dissection

A
  • TEE if elevated Cr or contrast allergy
  • chest CT
  • MRI
22
Q

Trimethoprim SE

A
  • hyperkalemia 2/2 blockade of epithelial sodium channel @ collecting tubule
  • inhibits renal tubular secretion of Cr ==> artificial elevation of Cr
23
Q

Cat bite ppx

A

amoxicillin/clavulanate

24
Q

Adenosine use

A
  • management of patients w/narrow-QRS-complex tachycardia

- slows conduction through AV node

25
Q

Paroxysmal supraventricular tachycardia presentation

A
  • abrupt onset/offset
  • AVNRT, AVRT, atrial tachy, jxnl tachy
  • palpitations, dizziness, lightheadedness
  • SOB, diaphoresis, chest pain, presyncope
26
Q

Electrolytes in Cushing’s

A

hypernatremia

hypokalemia

27
Q

Dx of esophageal perforation

A
  • CXR
  • CT
  • water-soluble esophagogram
28
Q

Testing if idiopathic thrombocytopenic purpura

A

HIV and Hep C