UWorld_7.23 Flashcards

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1
Q

Inconclusive fast ==> ?

A

dx peritoneal lavage

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2
Q

Back pain red flags

A
  • age > 50
  • hx cancer
  • constitutional sx
  • nighttime pain ==> interrupted sleep
  • pain > 1 mo.
  • no response to prev. therapy
  • neuro sx
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3
Q

Anticholinergic poisoning sx

A
  • dry mouth.skin (“dry as a bone”
  • blurry vision/mydriasis (“blind as a bat”)
  • hyperthermia (“hot as a hare”)
  • urinary retention (“full as a flask”)
  • decreased bowel sounds
  • cutaneous vasodilation (“red as beet”)
  • AMS (“mad as a hatter”)
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4
Q

Tx anticholinergic poisoning

A

physostigmine = cholinesterase inhibitor

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5
Q

Laryngomalacia improves w/…

A

prone

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6
Q

Vascular ring presentation

A

-presents @

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7
Q

Management of infat/neonate meningitis

A
  • 3rd ge. cephalosporins (cefotaxine @ neonates, ceftriaxone @ older infants) + vancomycin
  • dexamethasone ==> less SN hearing loss
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8
Q

Euthyroid sick syndrome presentation

A
  • “low T3 syndrome”
  • decreased total/free T3
  • normal T4
  • normal TSH
  • occurs in pt.s w/ acute/severe illness
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9
Q

CGD mechanism/dx

A
  • PMN/phagocyte dysfxn

- dx: nitroblue or dihydrorhodamine 123 test

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10
Q

Wiscott-Aldrich syndrome presentation

A
  • X-linked R
  • eczema
  • thrombocytopenia
  • recurrent infections
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11
Q

Schistocytes indicate ?

A
  • microangiopathic hemolytic anemia (e.g. DIC, TTP, HUS)

- not assoc. w/splenomegaly

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12
Q

Presentation of autoimmune hemolytic anemia

A
  • normocytic anemia
  • reticulocytosis
  • splenomegaly
  • jaundice
  • elevated indirect bili, LDH, and decreased hapto
  • peripheral smear = spherocytes
  • (+) direct antiglobulin (Coombs) test w/IgG ==> warm
  • -(+) direct antiglobulin (Coombs) test w/IgM ==> cold
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13
Q

Causes of warm agg. AIHA

A
  • drugs (e.g. penicillin)
  • viral infections
  • autoimmune (e.g. SLE)
  • immunodeficiency
  • lymphoproliferative (e.g. CLL)
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14
Q

Tx warm agg. AIHA

A
  • steroids

- splenectomy if refractory

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15
Q

Causes of cold agg. AIHA

A
  • infections: MAC PNA, mono

- lymphoproliferative (e.g. CLL)

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16
Q

Tx of cold agg. AIHA

A
  • avoid cold temp.

- rituximab +/- fludarabine

17
Q

Hypercalcemia sx

A
  • fatigue
  • **constipation
  • depression
18
Q

Leukoreduced RBC purpose/use

A
  • chronic transfusions
  • CMV at-risk pts
  • potential transplant recipients
  • prev. FEBRILE NONHEMO transfusion rxn
19
Q

Washed RBC purpose/use

A
  • IgA def.
  • complement-dep./cold AIHA
  • allergic rxns
20
Q

Rash on face + periorbital edema + proximal muscle weakness ==> dx?

A

dermatomyositis

21
Q

Dermatomyositis presentation

A
  • cutaneous findings: facial rash, periorbital edema, chest/lateral neck rash
  • gottron’s papules = violaceous, slighlty scaly papules over joints
  • proximal m. weakness + elevated CPK
  • anti-Jo and anti-Mi-2
22
Q

PTU SE

A

agranulocytosis

23
Q

methimazole SE

A

agranulocytosis

24
Q

N/V after eating rice

A

bacillus cereus

25
Q

Lab findings in PCV

A
  • elevated Hb
  • leukocytosis, thrombocytosis
  • low EPO
  • JAK2 mutation +
26
Q

Friedrich Ataxia

A

xxxxxx

27
Q

Most common cause of intermittent tachy arrhythm. in non-structural heart dz?

A
  • paroxysmal supraventricular tachycardia

- accessory conduction through the AV node

28
Q

Self-management of PSVT

A

-vagal maneuvers: valsalva, carotid massage, immersion in cold water ==> slowing @ AV node

29
Q

Med management of PSVT

A

adenosine = short-acting AV node block

30
Q

Early complications of STEMI

A
  • reinfarct (hours - 2 days)
  • septal rupture (hours - 1 week)
  • free wall rupture (hours - 2 weeks)
  • post-infarct angina (hours - 1mo.)
31
Q

Late complications of STEMI

A
  • Papillary m. rupture (2 days - 1 week)
  • pericarditis (1 day - 3 mo.)
  • L. ventricular aneurysm (5 days - 3 mo.) ==> HF