Upper Gastrointestinal Bleeding Flashcards
Upper Gastrointestinal Bleeding (UGIB):
Saraiva, 2016
Intraluminal bleeding between the esophagus and the Treitz ligament
Most common cause (Saraiva, 2016):
Peptic ulcer
Substances that are risk factors:
Use of Alcohol, NSAIAs and anticoagulants
Esophageal causes:
Erosive esophagitis (15%), Esophagus varices, Ectopic varices and Mallory-Weiss Syndrome
Pathophysiology of the Non-variceal UGIB:
Esophageal/Gastroduodenal mucosa lesion -> erosion/ulceration -> UGIB
Pathophysiology of the Variceal UGIB:
Portal hypertension -> Varices -> rupture -> UGIB
Classification:
Non-variceal and Variceal
Presentation:
Hematemesis, Melena, Hematochezia, Epigastric pain and Presyncope
Most common symptom:
Melena (70-80%)
Diagnostic procedures:
Nasogastric Lavage and Endoscopy
When endoscopy should be performed?
First 24h after the UGIB, immediately after endotracheal intubation (if indicated) and hemodynamic stabilization
Forrest Endoscopic Classification:
Acute hemorrhage (Ia e Ib), Signs of recent hemorrhage (IIa, IIb e IIc) and Lesions without active bleeding (III)
Diagnóstico Diferencial:
Hemorragia digestiva baixa
Tratamento:
MOV -> Reposição volêmica -> Terapia endoscópica —> Terlipressina —> Balão esofágico —> Corrige coagulopatia —> TIPS —> Cirurgia ou Embolização transcutânea
*Somatostatina ou Octreotide/Vapreotide
Reposição volêmica:
SF 0,9% 1000-2000mL EV —> CH
Terapia endoscópica:
Clipagem ou Escleroterapia
Indicações de IBP:
Forrest 1a-2b
IBP:
Omeprazol 80mg EV em bolus -> 8mg/h por 72h
Plaq -50.000:
Concentrado de Plaquetas