Unit 4 - Psychopathology Flashcards

1
Q

The scientific study of mental disorders to better understand their genetic, biological, social, and psychological causes

A

psychopathology

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2
Q

Refers to symptoms that are present but should not be

A

positive symptoms

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3
Q

refers to characteristics of the individual that are absent but should be present

A

negative symptoms

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4
Q

refers to problems with processing and acting on external information

A

cognitive symptoms

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5
Q

Measuring genetic and environmental contributions to behavior (psychopathology)

A

Behavioral Genetics

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6
Q

_________ twins are more likely to have schizophrenia (50% concordance)

A

monozygotic

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7
Q

____________ model of schizophrenia states that schizophrenia results from a complex set of genetic and environmental interactions

A

Neurodevelopmental

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8
Q

________ represent times when stress may have stronger effects

A

sensitive periods

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9
Q

The _________ period refers to the early phase or onset of a mental health disorder.

A

prodromal

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10
Q

____% of those who enter the prodromal phase develop a psychotic disorder

A

33%

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11
Q

Patients with schizophrenia have enlarged ____________.

A

cerebral ventricles

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12
Q

Patients with schizophrenia have abnormalities in the structure and function of the ____________ and accelerated cortical __________.

A

corpus callosum, thinning

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13
Q

____________ antipsychotics (first generation) act as selective antagonists of dopamine receptors.

A

traditional

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14
Q

Traditional antipsychotics reduce _________ symptoms of schizophrenia.

A

positive

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15
Q

___________ antipsychotics (second generation) target both dopaminergic and serotonergic receptors

A

Atypical

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16
Q

Atypical antipsychotics alleviate some of the _________ side effects of traditional antipsychotics, but lead to more weight gain.

A

motor

17
Q

The __________ hypothesis of schizophrenia states that schizophrenia is due to an excess of DA D2 neurotransmission

A

dopamine

18
Q

The _________ hypothesis of schizophrenia states that schizophrenia is due to under-activation of glutamate receptors which leads to an imbalance in excitatory and inhibitory brain activity

A

glutamate

19
Q

Heritability combines with __________ factors to determine whether depression will be present.

A

environmental

20
Q

Amygdala, insula, and cingulate activation increases during _________ processing in depressed patients.

A

emotion

21
Q

___________ prefrontal cortex activity decreased during emotion and attention tasks in depressed patients.

A

dorsolateral

22
Q

Nucleus accumbens/ventral striatum responses are blunted during ________ tasks in depressed patients.

A

reward

23
Q

There is cortical ___________ in depressed patients.

A

thinning

24
Q

Antidepressants generally increase synaptic transmission of ______________

A

monoamines

25
Q

The __________ hypothesis of depression states that depression is associated with too little stimulation at monoamine synapses.

A

monoamine

26
Q

__________ block enzymatic degradation of dopamine, serotonin, and norepinephrine

A

Monoamine oxidase (MAO)

27
Q

____________ antidepressants block reuptake of serotonin and norepinephrine

A

tricyclic

28
Q

____________ inhibitors (e.g., SSRIs, prozac, zoloft) act specifically at serotonergic synapses.

A

Selective serotonin reuptake

29
Q

Psychotherapy aimed at correcting negative thinking and consciously changing behaviors as a way of changing feelings

A

Cognitive behavioral therapy (CBT)

30
Q

A strong electrical current is passed through the entire brain, causing a seizure

A

Electroconvulsive therapy

31
Q

Transiently inhibits or facilitates cortical activity in a targeted location

A

Transcranial Magnetic Stimulation