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Pharmacology > Unit 3- Dermatopharmacology > Flashcards

Unit 3- Dermatopharmacology Flashcards

1
Q

Topical Absorption

A

Between stratum corneum cells, through hair follicles, through sweat or sebaceous glands

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2
Q

Skin Permeability

A

Drugs must be lipophilic, heavily haired animals have better absorption

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3
Q

Vehicle

A

Substance with the active agent to be administered

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4
Q

Antiseborrheics

A

Keratolytics and keratoplastics

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5
Q

Keratolytics

A

Hydrate and soften stratum corneum to promote mechanical removal

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6
Q

Keratoplastics

A

Normalize keratinization by slowing basal cell proliferation

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7
Q

Salicylic Acid

A

Keratolytic and keratoplastic, antimicrobial and antipruritic

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8
Q

Sulfur

A

Keratolytic and keratoplastic, follicular flushing action, antibacterial, antipruritic

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9
Q

Coal Tar

A

Keratolytic and keratoplastic, degreasing, not safe for felines

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10
Q

Benzoyl Peroxide

A

Keratolytic, degreasing, follicular flushing, bactericidal, oxidizer

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11
Q

Resorcinol

A

Keratolytic, antimicrobial, hydrates keratin

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12
Q

Selenium Sulfide

A

Keratolytic and keratoplastic, slows cell proliferation, can irritate mucous membrane

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13
Q

Itching Sensation Substitution

A

Menthol, camphor, warm soak, ice bath

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14
Q

Skin Protection

A

Protect from scratching, biting, irritant, humidity, temp

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15
Q

Anesthetize Peripheral Nerves

A

Local anesthetics, can cause allergic sensitization

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16
Q

Glucocorticoids

A

Topical or oral use for pruritus

17
Q

Escharotics

A

Precipitate proteins to form a crust and then scar

18
Q

Irritants

A

Mask pain by milder pain, induce healing action

19
Q

Candida Treatment

A

Amphotericin B, Clotrimazole, Miconazole

20
Q

Malassezia Treatment

A

Chlorohex and ketoconazole, Clotrimazole, Miconazole, Thiabendazole

21
Q

Dermatophyte Treatment

A

Clotrimazole, Miconazole, Nystatin, Sulfur, Thiabendazole

22
Q

Transdermals Hazardous to Humans

A

DMSO, anticancer, nitroglycerine, antiparasitics

23
Q

Nitroglicerin

A

Relaxes vascular smooth muscle, treats cardiogenic edema

24
Q

Fentanyl

A

Narcotic

Pharmacology (32 decks)

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