Tumor Markers Flashcards
Tumor marker: Alkaline phosphatase
Metastases to bone or liver
Paget dse of bone
Seminoma (placental ALP)
Tumor marker: alpha-fetoprotein
Hepatocellular carcinoma, hepatoblastoma
Yolk sac tumor, mixed germ cell tumor
Tumor marker: Beta-hCG
Hydatidiform moles
Choriocarcinomas (gestational trophoblastic dse)
Testicular cancer, mixed germ cell tumor
Tumor marker: CA 15-3, CA 27-29
Breast cancer
Tumor marker: CA 19-9
Pancreatic adenoCA
Tumor marker: CA 125
Ovarian cancer
Tumor marker: Calcitonin
Medullary thyroid CA
Tumor marker: CEA (carcinoembryonic antigen)
Nonspecific.
Colorectal, pancreatic cancers
Also gastric, breast, medullary thyroid CA
Tumor marker: Chromogranin
Neuroendocrine tumors/carcinoids
Tumor marker: PSA (prostate specific antigen)
Prostate cancer
Also elevated in BPH, prostatitis