Tumor Markers Flashcards

1
Q

Tumor marker: Alkaline phosphatase

A

Metastases to bone or liver
Paget dse of bone
Seminoma (placental ALP)

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2
Q

Tumor marker: alpha-fetoprotein

A

Hepatocellular carcinoma, hepatoblastoma

Yolk sac tumor, mixed germ cell tumor

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3
Q

Tumor marker: Beta-hCG

A

Hydatidiform moles
Choriocarcinomas (gestational trophoblastic dse)
Testicular cancer, mixed germ cell tumor

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4
Q

Tumor marker: CA 15-3, CA 27-29

A

Breast cancer

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5
Q

Tumor marker: CA 19-9

A

Pancreatic adenoCA

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6
Q

Tumor marker: CA 125

A

Ovarian cancer

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7
Q

Tumor marker: Calcitonin

A

Medullary thyroid CA

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8
Q

Tumor marker: CEA (carcinoembryonic antigen)

A

Nonspecific.
Colorectal, pancreatic cancers
Also gastric, breast, medullary thyroid CA

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9
Q

Tumor marker: Chromogranin

A

Neuroendocrine tumors/carcinoids

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10
Q

Tumor marker: PSA (prostate specific antigen)

A

Prostate cancer

Also elevated in BPH, prostatitis

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